C. Diff Quik Chek complete enzyme immunoassay provides a reliable first-line method for detection of Clostridium difficile in stool specimens

Criziel D. Quinn, Susan E. Sefers, Wisal Babiker, Ying He, Romina Alcabasa, Charles W. Stratton, Karen C. Carroll, Yi Wei Tang

Research output: Contribution to journalArticle

Abstract

We evaluated a single membrane device assay for simultaneously detecting both Clostridium difficile glutamate dehydrogenase (GDH) and toxin A/B antigens against a standard that combines two PCR assays and cytotoxigenic culture. Results showing dual GDH and toxin A/B antigen positives and negatives can be reported immediately as true positives and negatives, respectively. Specimens with discrepant results for GDH and toxins A/B, which comprised 13.2% of the specimens, need to be retested.

Original languageEnglish (US)
Pages (from-to)603-605
Number of pages3
JournalJournal of clinical microbiology
Volume48
Issue number2
DOIs
StatePublished - Feb 2010

ASJC Scopus subject areas

  • Microbiology (medical)

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