Abstract
Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interacts with hydroxymethyl-CpG.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 940-942 |
| Number of pages | 3 |
| Journal | Cell |
| Volume | 152 |
| Issue number | 5 |
| DOIs | |
| State | Published - Feb 28 2013 |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
By hook or by crook : Multifaceted DNA-binding properties of MeCP2. / Shin, Jaehoon; Ming, Guo Li; Song, Hongjun.
In: Cell, Vol. 152, No. 5, 28.02.2013, p. 940-942.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - By hook or by crook
T2 - Multifaceted DNA-binding properties of MeCP2
AU - Shin, Jaehoon
AU - Ming, Guo Li
AU - Song, Hongjun
PY - 2013/2/28
Y1 - 2013/2/28
N2 - Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interacts with hydroxymethyl-CpG.
AB - Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interacts with hydroxymethyl-CpG.
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UR - http://www.scopus.com/inward/citedby.url?scp=84874779554&partnerID=8YFLogxK
U2 - 10.1016/j.cell.2013.02.017
DO - 10.1016/j.cell.2013.02.017
M3 - Article
C2 - 23452844
AN - SCOPUS:84874779554
VL - 152
SP - 940
EP - 942
JO - Cell
JF - Cell
SN - 0092-8674
IS - 5
ER -