By hook or by crook: Multifaceted DNA-binding properties of MeCP2

Jaehoon Shin; Guo Li Ming; Hongjun Song

doi:10.1016/j.cell.2013.02.017

By hook or by crook: Multifaceted DNA-binding properties of MeCP2

Jaehoon Shin, Guo Li Ming, Hongjun Song

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interacts with hydroxymethyl-CpG.

Original language	English (US)
Pages (from-to)	940-942
Number of pages	3
Journal	Cell
Volume	152
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2013.02.017
State	Published - Feb 28 2013

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1016/j.cell.2013.02.017

Cite this

@article{b294961679674e439db2bc5afc61b59a,

title = "By hook or by crook: Multifaceted DNA-binding properties of MeCP2",

abstract = "Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mell{\'e}n et al. find the methyl-CpG-binding domain of MeCP2 interacts with hydroxymethyl-CpG.",

author = "Jaehoon Shin and Ming, {Guo Li} and Hongjun Song",

year = "2013",

month = feb,

day = "28",

doi = "10.1016/j.cell.2013.02.017",

language = "English (US)",

volume = "152",

pages = "940--942",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - By hook or by crook

T2 - Multifaceted DNA-binding properties of MeCP2

AU - Shin, Jaehoon

AU - Ming, Guo Li

AU - Song, Hongjun

PY - 2013/2/28

Y1 - 2013/2/28

N2 - Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interacts with hydroxymethyl-CpG.

AB - Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interacts with hydroxymethyl-CpG.

UR - http://www.scopus.com/inward/record.url?scp=84874779554&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84874779554&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2013.02.017

DO - 10.1016/j.cell.2013.02.017

M3 - Article

C2 - 23452844

AN - SCOPUS:84874779554

VL - 152

SP - 940

EP - 942

JO - Cell

JF - Cell

SN - 0092-8674

IS - 5

ER -

By hook or by crook: Multifaceted DNA-binding properties of MeCP2

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this