Bursicon as a potential target for insect control

Shengzhang Dong, Qisheng Song

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Bursicon is an insect heterodimeric neuropeptide hormone which binds to a specific G protein-coupled receptor, Drosophila leucine-rich repeats-containing G-protein-coupled receptor 2 (DLGR2) and regulates various aspects of cuticle tanning (sclerotization and melanization) and wing expansion in diverse insect orders. Bursicon was discovered 50 years ago by Gottfried Fraenkel using the blowfly Calliphora erythrocephala in a neck-ligated fly assay. Over the last few years, there has been a tremendous increase in our knowledge of bursicon molecular structure and signaling pathway due to recent advances in genomics, proteomics and genetic analysis, combined with physiological and behavior analysis. Insect neuropeptides, which are released from neurosecretory cells in the insect central nervous system (CNS), regulate virtually all aspects of insect life and would appear to be excellent candidates for development of new methods for pest control. As a critical neuropeptide during the process of insect molting cycle, bursicon could also be used for the design of novel, safe and selective compounds to control pests. Here, we will review recent advances in bursicon research and developments of neuropeptides for pest control, and then discuss the possibilities of bursicon as a target for pest control.

Original languageEnglish (US)
Title of host publicationAdvanced Technologies for Managing Insect Pests
PublisherSpringer Netherlands
Pages83-105
Number of pages23
ISBN (Electronic)9789400744974
ISBN (Print)940074496X, 9789400744967
DOIs
StatePublished - Oct 1 2013

Fingerprint

Insect Control
insect control
Insects
Pest Control
neuropeptides
Neuropeptides
pest control
insects
sclerotization
CCR10 Receptors
Tanning
Calliphora vicina
Molting
neurosecretory cells
melanization
Calliphoridae
G-Protein-Coupled Receptors
Genomics
research and development
Molecular Structure

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Dong, S., & Song, Q. (2013). Bursicon as a potential target for insect control. In Advanced Technologies for Managing Insect Pests (pp. 83-105). Springer Netherlands. https://doi.org/10.1007/978-94-007-4497-4_5

Bursicon as a potential target for insect control. / Dong, Shengzhang; Song, Qisheng.

Advanced Technologies for Managing Insect Pests. Springer Netherlands, 2013. p. 83-105.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dong, S & Song, Q 2013, Bursicon as a potential target for insect control. in Advanced Technologies for Managing Insect Pests. Springer Netherlands, pp. 83-105. https://doi.org/10.1007/978-94-007-4497-4_5
Dong S, Song Q. Bursicon as a potential target for insect control. In Advanced Technologies for Managing Insect Pests. Springer Netherlands. 2013. p. 83-105 https://doi.org/10.1007/978-94-007-4497-4_5
Dong, Shengzhang ; Song, Qisheng. / Bursicon as a potential target for insect control. Advanced Technologies for Managing Insect Pests. Springer Netherlands, 2013. pp. 83-105
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