On the basis of performed studies the following observations indicate that there is a bursa-independent origin of lymphocytes with Fc IgG receptors: the first appearance of Fc positive cells is in fetal liver and bone marrow; a relative low percentage of Fc receptor cells, as compared to B cells, occurs in the bursa during the embryonic and post-hatching period; a far lower percentage of Fc positive cells than B cells is found in the spleen; a normal level of Fc positive cells occurs in bursectomized birds; (and, a majority of these cells do not possess thymic or bursa antigen or surface immunoglobulin.
|Original language||English (US)|
|Number of pages||4|
|Journal||Archivum Immunologiae et Therapiae Experimentalis|
|Publication status||Published - 1979|
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