Burkitt's and Other Non-Hodgkin's Lymphomas in Adults Exposed to a Visitor from Africa

Seymour Grufferman, Nancy Raab-Traub, Kay Marvin, Michael J. Borowitz, Joseph S. Pagano

Research output: Contribution to journalArticlepeer-review

Abstract

DISEASE clustering, the occurrence of cases that are close together in time and space, is often believed to suggest an infectious cause.1,2 Despite numerous anecdotal reports of cancer clusters, Burkitt's lymphoma is the only human cancer for which there is clear-cut statistical evidence of time—space clustering.2 3 4 In general, reports of cancer clusters are uninformative, since most cancers have long, variable, or unknown latency periods between etiologic exposure and manifestation of the disease.2,4,5 A typical reported cluster is characterized by proximity in the time of diagnosis and in the residence of patients at diagnosis. However, the etiologic exposure may have occurred.

Original languageEnglish (US)
Pages (from-to)1525-1529
Number of pages5
JournalNew England Journal of Medicine
Volume313
Issue number24
DOIs
StatePublished - Dec 12 1985
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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