Burden of preoperative cardiovascular disease risk factors on breast cancer surgery outcomes

Brian Z. Huang, Melissa Camp

Research output: Contribution to journalArticlepeer-review


Background: Cardiovascular comorbidities have been studied sporadically in breast cancer surgery. No study has provided a comprehensive assessment of the severity and relative influence of preoperative cardiac risk factors on surgical outcomes. Methods: 78,338 breast cancer surgery patients were identified from the 2006 to 2012 National Surgical Quality Improvement Program (NSQIP) database. We estimated the impact of chronic conditions (diabetes, hypertension, obesity, smoking), acute cardiac events (myocardial infarction, congestive heart disease, angina), and past cardiac procedures (cardiac surgery, percutaneous coronary intervention) on 30-day postoperative complications, reoperation, and readmission. Results: Nearly 65% of patients had chronic conditions, trend<0.001). Conclusions: Cardiovascular disease has a significant impact on outcomes even in minimal-risk breast cancer surgery. J. Surg. Oncol. 2016;114:144–149.

Original languageEnglish (US)
Pages (from-to)144-149
Number of pages6
JournalJournal of Surgical Oncology
Issue number2
StatePublished - Aug 1 2016


  • 30-day postoperative outcomes
  • breast cancer surgery
  • cardiovascular disease
  • complications
  • readmission
  • reoperation

ASJC Scopus subject areas

  • Surgery
  • Oncology


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