Building the bionic T cell

Research output: Contribution to journalShort surveypeer-review


Adoptive T cell transfer studies in mice and in cancer patients have shown substantial potential, but also major barriers, for successful therapeutic outcomes. A new strategy may overcome some of these barriers. T cells can now be engineered with 'autocostimulation' properties along with chimeric receptors specific for tumor antigens (pages 1440-1449).

Original languageEnglish (US)
Pages (from-to)1411-1413
Number of pages3
JournalNature medicine
Issue number12
StatePublished - Dec 1 2007

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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