Building a better mosquito: Identifying the genes enabling malaria and dengue fever resistance in A. gambiae and A. aegypti mosquitoes

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Abstract

In this interview, George Dimopoulos focuses on the physiological mechanisms used by mosquitoes to combat Plasmodium falciparum and dengue virus infections. Explanation is given for how key refractory genes, those genes conferring resistance to vector pathogens, are identified in the mosquito and how this knowledge can be used to generate transgenic mosquitoes that are unable to carry the malaria parasite or dengue virus.

Original languageEnglish (US)
Article numbere233
JournalJournal of Visualized Experiments
Issue number5
DOIs
StatePublished - Jun 2007

ASJC Scopus subject areas

  • Neuroscience(all)
  • Chemical Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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