Abstract
Fighting the resistance: Biodegradable and injectable/moldable hydrogels with hierarchical nanostructures (see picture) were made with broad-spectrum antimicrobial activities and biofilm-disruption capability. They demonstrate no cytotoxicity in vitro, and show excellent skin biocompatibility in animals. These hydrogels have great potential for clinical use in prevention and treatment of various multidrug-resistant infections.
Original language | English (US) |
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Pages (from-to) | 674-678 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 52 |
Issue number | 2 |
DOIs | |
State | Published - Jan 7 2013 |
Externally published | Yes |
Keywords
- biofilms
- electron microscopy
- gels
- noncovalent interactions
- supramolecular chemistry
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)