Brief Report: Age-Disparate Relationships and HIV Prevalence Among Never Married Women in Rakai, Uganda

George Mwinnyaa, Ronald H Gray, Mary Grabowski, Joseph Ssekasanvu, Anthony Ndyanabo, Robert Ssekubugu, Joseph Kagaayi, Godfrey Kigozi, Gertrude Nakigozi, David M. Serwadda, Oliver B. Laeyendecker

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Age-disparate relationships are associated with increased HIV prevalence. We determined whether the frequency of age-disparate relationships in never married women changed over time and whether they are associated with HIV prevalence in Rakai, Uganda.

METHODS: A total of 10,061 never married women, aged 15-49 years, in the Rakai Community Cohort Study provided information on the age of their male sexual partners from 1997 to 2013. Logistic regression was used to assess trends in age-disparate relationships (≥5 years) between never married women and their male partners. Log-binomial regression was used to estimate adjusted prevalence ratios (adjPR) of HIV prevalence associated with age-disparate relationships.

RESULTS: Two thousand nine hundred ninety-nine women (30%) had a male partner ≥5 years older, which remained stable over time. The prevalence of HIV among women in age-disparate relationships was 14%, 10% for women in relationships with men 0-4 years older (adjPR 1.36, 95% confidence interval: 1.22 to 1.53) not controlling women's age; however, after age adjustment, the impact of age-disparate relationships on HIV prevalence was attenuated. Age-disparate relationships were associated with increased HIV prevalence among women aged 15-17 years (adjPR 1.83, 95% confidence interval: 1.10 to 3.17), but not in other age groups.

CONCLUSIONS: The frequency of age-disparate relationships among never married women was unchanged over a 15-year period in Rakai, Uganda. Age-disparate relationships were associated with increased HIV prevalence among adolescents aged 15-17 years, but not older women.

Original languageEnglish (US)
Pages (from-to)430-434
Number of pages5
JournalJournal of acquired immune deficiency syndromes (1999)
Volume79
Issue number4
DOIs
StatePublished - Dec 1 2018

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Uganda
HIV
Confidence Intervals
Social Adjustment
Sexual Partners
Cohort Studies
Age Groups
Logistic Models

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)

Cite this

Brief Report : Age-Disparate Relationships and HIV Prevalence Among Never Married Women in Rakai, Uganda. / Mwinnyaa, George; Gray, Ronald H; Grabowski, Mary; Ssekasanvu, Joseph; Ndyanabo, Anthony; Ssekubugu, Robert; Kagaayi, Joseph; Kigozi, Godfrey; Nakigozi, Gertrude; Serwadda, David M.; Laeyendecker, Oliver B.

In: Journal of acquired immune deficiency syndromes (1999), Vol. 79, No. 4, 01.12.2018, p. 430-434.

Research output: Contribution to journalArticle

Mwinnyaa, George ; Gray, Ronald H ; Grabowski, Mary ; Ssekasanvu, Joseph ; Ndyanabo, Anthony ; Ssekubugu, Robert ; Kagaayi, Joseph ; Kigozi, Godfrey ; Nakigozi, Gertrude ; Serwadda, David M. ; Laeyendecker, Oliver B. / Brief Report : Age-Disparate Relationships and HIV Prevalence Among Never Married Women in Rakai, Uganda. In: Journal of acquired immune deficiency syndromes (1999). 2018 ; Vol. 79, No. 4. pp. 430-434.
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AU - Gray, Ronald H

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AU - Ssekasanvu, Joseph

AU - Ndyanabo, Anthony

AU - Ssekubugu, Robert

AU - Kagaayi, Joseph

AU - Kigozi, Godfrey

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AU - Serwadda, David M.

AU - Laeyendecker, Oliver B.

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N2 - BACKGROUND: Age-disparate relationships are associated with increased HIV prevalence. We determined whether the frequency of age-disparate relationships in never married women changed over time and whether they are associated with HIV prevalence in Rakai, Uganda.METHODS: A total of 10,061 never married women, aged 15-49 years, in the Rakai Community Cohort Study provided information on the age of their male sexual partners from 1997 to 2013. Logistic regression was used to assess trends in age-disparate relationships (≥5 years) between never married women and their male partners. Log-binomial regression was used to estimate adjusted prevalence ratios (adjPR) of HIV prevalence associated with age-disparate relationships.RESULTS: Two thousand nine hundred ninety-nine women (30%) had a male partner ≥5 years older, which remained stable over time. The prevalence of HIV among women in age-disparate relationships was 14%, 10% for women in relationships with men 0-4 years older (adjPR 1.36, 95% confidence interval: 1.22 to 1.53) not controlling women's age; however, after age adjustment, the impact of age-disparate relationships on HIV prevalence was attenuated. Age-disparate relationships were associated with increased HIV prevalence among women aged 15-17 years (adjPR 1.83, 95% confidence interval: 1.10 to 3.17), but not in other age groups.CONCLUSIONS: The frequency of age-disparate relationships among never married women was unchanged over a 15-year period in Rakai, Uganda. Age-disparate relationships were associated with increased HIV prevalence among adolescents aged 15-17 years, but not older women.

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