Breastfeeding and intelligence: A systematic review and meta-analysis

Bernardo L. Horta, Christian Loret De Mola, Cesar G. Victora

Research output: Contribution to journalArticle

Abstract

Aim This study was aimed at systematically reviewing evidence of the association between breastfeeding and performance in intelligence tests. Methods Two independent searches were carried out using Medline, LILACS, SCIELO and Web of Science. Studies restricted to infants and those where estimates were not adjusted for stimulation or interaction at home were excluded. Fixed- and random-effects models were used to pool the effect estimates, and a random-effects regression was used to assess potential sources of heterogeneity. Results We included 17 studies with 18 estimates of the relationship between breastfeeding and performance in intelligence tests. In a random-effects model, breastfed subjects achieved a higher IQ [mean difference: 3.44 points (95% confidence interval: 2.30; 4.58)]. We found no evidence of publication bias. Studies that controlled for maternal IQ showed a smaller benefit from breastfeeding [mean difference 2.62 points (95% confidence interval: 1.25; 3.98)]. In the meta-regression, none of the study characteristics explained the heterogeneity among the studies. Conclusion Breastfeeding is related to improved performance in intelligence tests. A positive effect of breastfeeding on cognition was also observed in a randomised trial. This suggests that the association is causal.

Original languageEnglish (US)
Pages (from-to)14-19
Number of pages6
JournalActa Paediatrica, International Journal of Paediatrics
Volume104
DOIs
StatePublished - Dec 1 2015
Externally publishedYes

Fingerprint

Breast Feeding
Intelligence
Meta-Analysis
Intelligence Tests
Confidence Intervals
Publication Bias
Cognition
Mothers

Keywords

  • Breastfeeding
  • Intelligence test
  • Meta-analysis
  • Systematic review

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Breastfeeding and intelligence : A systematic review and meta-analysis. / Horta, Bernardo L.; Loret De Mola, Christian; Victora, Cesar G.

In: Acta Paediatrica, International Journal of Paediatrics, Vol. 104, 01.12.2015, p. 14-19.

Research output: Contribution to journalArticle

Horta, Bernardo L. ; Loret De Mola, Christian ; Victora, Cesar G. / Breastfeeding and intelligence : A systematic review and meta-analysis. In: Acta Paediatrica, International Journal of Paediatrics. 2015 ; Vol. 104. pp. 14-19.
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