Breast sentinel lymph node navigation with three-dimensional computed tomography–lymphography: a 12-year study

Shigeru Yamamoto, Kazuyoshi Suga, Kazunari Maeda, Noriko Maeda, Kiyoshi Yoshimura, Masaaki Oka

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To evaluate the utility of three-dimensional (3D) computed tomography (CT)−lymphography (LG) breast sentinel lymph node navigation in our institute. Patients and methods: Between 2002 and 2013, we preoperatively identified sentinel lymph nodes (SLNs) in 576 clinically node-negative breast cancer patients with T1 and T2 breast cancer using 3D CT–LG method. SLN biopsy (SLNB) was performed in 557 of 576 patients using both the images of 3D CT–LG for guidance and the blue dye method. Results: Using 3D CT–LG, SLNs were visualized in 569 (99 %) of 576 patients. Of 569 patients, both lymphatic draining ducts and SLNs from the peritumoral and periareolar areas were visualized in 549 (96 %) patients. Only SLNs without lymphatic draining ducts were visualized in 20 patients. Drainage lymphatic pathways visualized with 3D CT–LG (549 cases) were classified into four patterns: single route/single SLN (355 cases, 65 %), multiple routes/single SLN (59 cases, 11 %) single route/multiple SLNs (62 cases, 11 %) and multiple routes/multiple SLNs (73 cases, 13 %). SLNs were detected in 556 (99.8 %) of 557 patients during SLNB. Conclusion: CT–LG is useful for preoperative visualization of SLNs and breast lymphatic draining routes. This preoperative method should contribute greatly to the easy detection of SLNs during SLNB.

Original languageEnglish (US)
Pages (from-to)456-462
Number of pages7
JournalBreast Cancer
Volume23
Issue number3
DOIs
StatePublished - May 1 2016
Externally publishedYes

Keywords

  • Breast cancer
  • Computed tomography
  • Lymphography
  • Sentinel lymph node

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Pharmacology (medical)

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