Breast-feeding and HIV-1 transmission in resource-limited settings

Mary Glenn Fowler, Marie Louise Newell

Research output: Contribution to journalArticle

Abstract

In many international settings, transmission of the HIV virus during lactation accounts for one third to one half of all HIV transmission from mothers to infants. Reduction of HIV transmission during lactation is one of the most pressing public health dilemmas confronting perinatal researchers, health policy makers, and HIV-infected women in many areas of the world. While results of clinical trials, laboratory and observational studies have increased our understanding of risk factors for breast-feeding transmission and the timing of postnatal transmission, there are no proven strategies known to reduce the risk of HIV transmission during breast-feeding for those HIV-infected women who opt to breast-feed in developing countries. Approaches to decreasing transmission of HIV through breast-feeding that will be studied include trials of combination antiretrovirals given to mothers during lactation. These research efforts using maternal antiretrovirals for perinatal HIV prevention during breast-feeding will interface with emerging plans for treatment programs in developing countries.

Original languageEnglish (US)
Pages (from-to)230-239
Number of pages10
JournalJournal of Acquired Immune Deficiency Syndromes
Volume30
Issue number2
StatePublished - Jun 1 2002
Externally publishedYes

Fingerprint

Breast Feeding
HIV-1
HIV
Lactation
Mothers
Developing Countries
Health Policy
Administrative Personnel
Observational Studies
Breast
Public Health
Research Personnel
Clinical Trials
Viruses
Research

ASJC Scopus subject areas

  • Virology
  • Immunology

Cite this

Breast-feeding and HIV-1 transmission in resource-limited settings. / Fowler, Mary Glenn; Newell, Marie Louise.

In: Journal of Acquired Immune Deficiency Syndromes, Vol. 30, No. 2, 01.06.2002, p. 230-239.

Research output: Contribution to journalArticle

@article{c7c08523619c42d7bc762044f5332a67,
title = "Breast-feeding and HIV-1 transmission in resource-limited settings",
abstract = "In many international settings, transmission of the HIV virus during lactation accounts for one third to one half of all HIV transmission from mothers to infants. Reduction of HIV transmission during lactation is one of the most pressing public health dilemmas confronting perinatal researchers, health policy makers, and HIV-infected women in many areas of the world. While results of clinical trials, laboratory and observational studies have increased our understanding of risk factors for breast-feeding transmission and the timing of postnatal transmission, there are no proven strategies known to reduce the risk of HIV transmission during breast-feeding for those HIV-infected women who opt to breast-feed in developing countries. Approaches to decreasing transmission of HIV through breast-feeding that will be studied include trials of combination antiretrovirals given to mothers during lactation. These research efforts using maternal antiretrovirals for perinatal HIV prevention during breast-feeding will interface with emerging plans for treatment programs in developing countries.",
author = "Fowler, {Mary Glenn} and Newell, {Marie Louise}",
year = "2002",
month = "6",
day = "1",
language = "English (US)",
volume = "30",
pages = "230--239",
journal = "Journal of Acquired Immune Deficiency Syndromes",
issn = "1525-4135",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Breast-feeding and HIV-1 transmission in resource-limited settings

AU - Fowler, Mary Glenn

AU - Newell, Marie Louise

PY - 2002/6/1

Y1 - 2002/6/1

N2 - In many international settings, transmission of the HIV virus during lactation accounts for one third to one half of all HIV transmission from mothers to infants. Reduction of HIV transmission during lactation is one of the most pressing public health dilemmas confronting perinatal researchers, health policy makers, and HIV-infected women in many areas of the world. While results of clinical trials, laboratory and observational studies have increased our understanding of risk factors for breast-feeding transmission and the timing of postnatal transmission, there are no proven strategies known to reduce the risk of HIV transmission during breast-feeding for those HIV-infected women who opt to breast-feed in developing countries. Approaches to decreasing transmission of HIV through breast-feeding that will be studied include trials of combination antiretrovirals given to mothers during lactation. These research efforts using maternal antiretrovirals for perinatal HIV prevention during breast-feeding will interface with emerging plans for treatment programs in developing countries.

AB - In many international settings, transmission of the HIV virus during lactation accounts for one third to one half of all HIV transmission from mothers to infants. Reduction of HIV transmission during lactation is one of the most pressing public health dilemmas confronting perinatal researchers, health policy makers, and HIV-infected women in many areas of the world. While results of clinical trials, laboratory and observational studies have increased our understanding of risk factors for breast-feeding transmission and the timing of postnatal transmission, there are no proven strategies known to reduce the risk of HIV transmission during breast-feeding for those HIV-infected women who opt to breast-feed in developing countries. Approaches to decreasing transmission of HIV through breast-feeding that will be studied include trials of combination antiretrovirals given to mothers during lactation. These research efforts using maternal antiretrovirals for perinatal HIV prevention during breast-feeding will interface with emerging plans for treatment programs in developing countries.

UR - http://www.scopus.com/inward/record.url?scp=0036603337&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036603337&partnerID=8YFLogxK

M3 - Article

C2 - 12045686

AN - SCOPUS:0036603337

VL - 30

SP - 230

EP - 239

JO - Journal of Acquired Immune Deficiency Syndromes

JF - Journal of Acquired Immune Deficiency Syndromes

SN - 1525-4135

IS - 2

ER -