Breast cancer mortality among female radiologic technologists in the United States

Aparna K. Mohan, Michael Hauptmann, Martha S. Linet, Elaine Ron, Jay H. Lubin, D. Michal Freedman, Bruce H. Alexander, John D. Boice, Michele Morin Doody, Genevieve Matanoski

Research output: Contribution to journalArticle

Abstract

We evaluated breast cancer mortality through 1997 among 69 525 female radiologic technologists who were certified in the United States from 1926 through 1982 and who responded to our questionnaire. Risk of breast cancer mortality was examined according to work history and practices and was adjusted for known risk factors. Breast cancer mortality risk was highest among women who were first employed as radiologic technologists prior to 1940 (relative risk [RR] = 2.92, 95% confidence interval [CI] = 1.22 to 7.00) compared with risk of those first employed in 1960 or later and declined with more recent calendar year of first employment (P for trend = .002). Breast cancer mortality risk increased with increasing number of years of employment as a technologist prior to 1950 (P for trend = .018). However, risk was not associated with the total number of years a woman worked as a technologist. Technologists who first performed fluoroscopy (RR = 1.69, 95% CI = 1.02 to 3.11) and multifilm procedures (RR = 1.87, 95% CI = 1.04 to 3.34) before 1950 had statistically significantly elevated risks compared with technologists who first performed these procedures in 1960 or later. The high risks of breast cancer mortality for women exposed to occupational radiation prior to 1950 and the subsequent decline in risk are consistent with the dramatic reduction in recommended radiation exposure limits over time.

Original languageEnglish (US)
Pages (from-to)943-948
Number of pages6
JournalJournal of the National Cancer Institute
Volume94
Issue number12
StatePublished - Jun 19 2002

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Breast Neoplasms
Mortality
Confidence Intervals
Fluoroscopy
History
Radiation

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Mohan, A. K., Hauptmann, M., Linet, M. S., Ron, E., Lubin, J. H., Freedman, D. M., ... Matanoski, G. (2002). Breast cancer mortality among female radiologic technologists in the United States. Journal of the National Cancer Institute, 94(12), 943-948.

Breast cancer mortality among female radiologic technologists in the United States. / Mohan, Aparna K.; Hauptmann, Michael; Linet, Martha S.; Ron, Elaine; Lubin, Jay H.; Freedman, D. Michal; Alexander, Bruce H.; Boice, John D.; Doody, Michele Morin; Matanoski, Genevieve.

In: Journal of the National Cancer Institute, Vol. 94, No. 12, 19.06.2002, p. 943-948.

Research output: Contribution to journalArticle

Mohan, AK, Hauptmann, M, Linet, MS, Ron, E, Lubin, JH, Freedman, DM, Alexander, BH, Boice, JD, Doody, MM & Matanoski, G 2002, 'Breast cancer mortality among female radiologic technologists in the United States', Journal of the National Cancer Institute, vol. 94, no. 12, pp. 943-948.
Mohan AK, Hauptmann M, Linet MS, Ron E, Lubin JH, Freedman DM et al. Breast cancer mortality among female radiologic technologists in the United States. Journal of the National Cancer Institute. 2002 Jun 19;94(12):943-948.
Mohan, Aparna K. ; Hauptmann, Michael ; Linet, Martha S. ; Ron, Elaine ; Lubin, Jay H. ; Freedman, D. Michal ; Alexander, Bruce H. ; Boice, John D. ; Doody, Michele Morin ; Matanoski, Genevieve. / Breast cancer mortality among female radiologic technologists in the United States. In: Journal of the National Cancer Institute. 2002 ; Vol. 94, No. 12. pp. 943-948.
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