Breast cancer

Factors associated with stage at diagnosis in black and white women

Carrie P. Hunter, Carol K. Redmond, Vivien W. Chen, Donald F. Austin, Raymond S. Greenberg, Pelayo Correa, Hyman B. Muss, Michele R. Forman, Margaret N. Wesley, Robert S. Blacklow, Robert J Kurman, James J. Dignam, Brenda K. Edwards, Sam Shapiro

Research output: Contribution to journalArticle

Abstract

Background: Numerous studies have reported differences in cancer staging at diagnosis and in survival between Black and White patients with breast cancer. Utilizing data obtained from the National Cancer Institute's (NCI's) Black/White Cancer Survival Study for the period 1985-1986, a new study is presented here that systematically examines multiple explanatory factors (e.g., lack of mammograms) associated with these cancerstaging differences. Purpose: We evaluated within a single study the relationship of selected demographic, lifestyle, antecedent medical experiences, and health care access factors to cancer staging at diagnosis in Black and White breast cancer patients. Methods: Data utilized in this population-based cohort study of 1222 eligible women (649 Black and 573 White) newly diagnosed for the period 1985-1986 with histologically confirmed primary breast cancer were obtained from the NCI's Black/White Cancer Survival Study. Sources of data included abstracts of hospital medical records, central review of histology slides by a study consultant pathologist, and patient interviews obtained from three metropolitan areas: Atlanta, New Orleans, and San Francisco Oakland. Within each area, 70% of all Black incident cases were randomly selected, and a sample of White cases, frequency matched by age groups (20-49 years, 50-64 years, and 65-79 years), was selected for comparison. Stage of breast cancer at diagnosis was classified according to the international tumor-lymph nodemetastases (TNM) system. Statistical models utilized in this study included the log-linear and polychotomous logistic regression with multiple predictor variables. Results: Factors associated with cancer staging were differentially expressed in Blacks and Whites. Indicators of access to health care, a lack of mammograms, and an increased body mass index significantly (pNO cancer among Blacks compared with Whites (odds ratio reduction from 2.19 to 1.68). Conclusion: These findings suggest that no single factor or group of factors can explain more than half of the race-stage differences noted in this study with respect to Black and White breast cancer patients. [J Nat) Cancer Inst 85:1129-1137, 1993]

Original languageEnglish (US)
Pages (from-to)1129-1137
Number of pages9
JournalJournal of the National Cancer Institute
Volume85
Issue number14
DOIs
StatePublished - Jul 21 1993

Fingerprint

Breast Cancer
Health care
Cancer
Breast Neoplasms
Neoplasm Staging
Histology
Health Services Accessibility
National Cancer Institute (U.S.)
Neoplasms
Logistics
Tumors
Mammogram
Survival
Healthcare
San Francisco
Hospital Records
Information Storage and Retrieval
Statistical Models
Lymph
Consultants

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Oncology
  • Cancer Research

Cite this

Hunter, C. P., Redmond, C. K., Chen, V. W., Austin, D. F., Greenberg, R. S., Correa, P., ... Shapiro, S. (1993). Breast cancer: Factors associated with stage at diagnosis in black and white women. Journal of the National Cancer Institute, 85(14), 1129-1137. https://doi.org/10.1093/jnci/85.14.1129

Breast cancer : Factors associated with stage at diagnosis in black and white women. / Hunter, Carrie P.; Redmond, Carol K.; Chen, Vivien W.; Austin, Donald F.; Greenberg, Raymond S.; Correa, Pelayo; Muss, Hyman B.; Forman, Michele R.; Wesley, Margaret N.; Blacklow, Robert S.; Kurman, Robert J; Dignam, James J.; Edwards, Brenda K.; Shapiro, Sam.

In: Journal of the National Cancer Institute, Vol. 85, No. 14, 21.07.1993, p. 1129-1137.

Research output: Contribution to journalArticle

Hunter, CP, Redmond, CK, Chen, VW, Austin, DF, Greenberg, RS, Correa, P, Muss, HB, Forman, MR, Wesley, MN, Blacklow, RS, Kurman, RJ, Dignam, JJ, Edwards, BK & Shapiro, S 1993, 'Breast cancer: Factors associated with stage at diagnosis in black and white women', Journal of the National Cancer Institute, vol. 85, no. 14, pp. 1129-1137. https://doi.org/10.1093/jnci/85.14.1129
Hunter, Carrie P. ; Redmond, Carol K. ; Chen, Vivien W. ; Austin, Donald F. ; Greenberg, Raymond S. ; Correa, Pelayo ; Muss, Hyman B. ; Forman, Michele R. ; Wesley, Margaret N. ; Blacklow, Robert S. ; Kurman, Robert J ; Dignam, James J. ; Edwards, Brenda K. ; Shapiro, Sam. / Breast cancer : Factors associated with stage at diagnosis in black and white women. In: Journal of the National Cancer Institute. 1993 ; Vol. 85, No. 14. pp. 1129-1137.
@article{4cfafdac8c0145738cb6e758afb3a87c,
title = "Breast cancer: Factors associated with stage at diagnosis in black and white women",
abstract = "Background: Numerous studies have reported differences in cancer staging at diagnosis and in survival between Black and White patients with breast cancer. Utilizing data obtained from the National Cancer Institute's (NCI's) Black/White Cancer Survival Study for the period 1985-1986, a new study is presented here that systematically examines multiple explanatory factors (e.g., lack of mammograms) associated with these cancerstaging differences. Purpose: We evaluated within a single study the relationship of selected demographic, lifestyle, antecedent medical experiences, and health care access factors to cancer staging at diagnosis in Black and White breast cancer patients. Methods: Data utilized in this population-based cohort study of 1222 eligible women (649 Black and 573 White) newly diagnosed for the period 1985-1986 with histologically confirmed primary breast cancer were obtained from the NCI's Black/White Cancer Survival Study. Sources of data included abstracts of hospital medical records, central review of histology slides by a study consultant pathologist, and patient interviews obtained from three metropolitan areas: Atlanta, New Orleans, and San Francisco Oakland. Within each area, 70{\%} of all Black incident cases were randomly selected, and a sample of White cases, frequency matched by age groups (20-49 years, 50-64 years, and 65-79 years), was selected for comparison. Stage of breast cancer at diagnosis was classified according to the international tumor-lymph nodemetastases (TNM) system. Statistical models utilized in this study included the log-linear and polychotomous logistic regression with multiple predictor variables. Results: Factors associated with cancer staging were differentially expressed in Blacks and Whites. Indicators of access to health care, a lack of mammograms, and an increased body mass index significantly (pNO cancer among Blacks compared with Whites (odds ratio reduction from 2.19 to 1.68). Conclusion: These findings suggest that no single factor or group of factors can explain more than half of the race-stage differences noted in this study with respect to Black and White breast cancer patients. [J Nat) Cancer Inst 85:1129-1137, 1993]",
author = "Hunter, {Carrie P.} and Redmond, {Carol K.} and Chen, {Vivien W.} and Austin, {Donald F.} and Greenberg, {Raymond S.} and Pelayo Correa and Muss, {Hyman B.} and Forman, {Michele R.} and Wesley, {Margaret N.} and Blacklow, {Robert S.} and Kurman, {Robert J} and Dignam, {James J.} and Edwards, {Brenda K.} and Sam Shapiro",
year = "1993",
month = "7",
day = "21",
doi = "10.1093/jnci/85.14.1129",
language = "English (US)",
volume = "85",
pages = "1129--1137",
journal = "Journal of the National Cancer Institute",
issn = "0027-8874",
publisher = "Oxford University Press",
number = "14",

}

TY - JOUR

T1 - Breast cancer

T2 - Factors associated with stage at diagnosis in black and white women

AU - Hunter, Carrie P.

AU - Redmond, Carol K.

AU - Chen, Vivien W.

AU - Austin, Donald F.

AU - Greenberg, Raymond S.

AU - Correa, Pelayo

AU - Muss, Hyman B.

AU - Forman, Michele R.

AU - Wesley, Margaret N.

AU - Blacklow, Robert S.

AU - Kurman, Robert J

AU - Dignam, James J.

AU - Edwards, Brenda K.

AU - Shapiro, Sam

PY - 1993/7/21

Y1 - 1993/7/21

N2 - Background: Numerous studies have reported differences in cancer staging at diagnosis and in survival between Black and White patients with breast cancer. Utilizing data obtained from the National Cancer Institute's (NCI's) Black/White Cancer Survival Study for the period 1985-1986, a new study is presented here that systematically examines multiple explanatory factors (e.g., lack of mammograms) associated with these cancerstaging differences. Purpose: We evaluated within a single study the relationship of selected demographic, lifestyle, antecedent medical experiences, and health care access factors to cancer staging at diagnosis in Black and White breast cancer patients. Methods: Data utilized in this population-based cohort study of 1222 eligible women (649 Black and 573 White) newly diagnosed for the period 1985-1986 with histologically confirmed primary breast cancer were obtained from the NCI's Black/White Cancer Survival Study. Sources of data included abstracts of hospital medical records, central review of histology slides by a study consultant pathologist, and patient interviews obtained from three metropolitan areas: Atlanta, New Orleans, and San Francisco Oakland. Within each area, 70% of all Black incident cases were randomly selected, and a sample of White cases, frequency matched by age groups (20-49 years, 50-64 years, and 65-79 years), was selected for comparison. Stage of breast cancer at diagnosis was classified according to the international tumor-lymph nodemetastases (TNM) system. Statistical models utilized in this study included the log-linear and polychotomous logistic regression with multiple predictor variables. Results: Factors associated with cancer staging were differentially expressed in Blacks and Whites. Indicators of access to health care, a lack of mammograms, and an increased body mass index significantly (pNO cancer among Blacks compared with Whites (odds ratio reduction from 2.19 to 1.68). Conclusion: These findings suggest that no single factor or group of factors can explain more than half of the race-stage differences noted in this study with respect to Black and White breast cancer patients. [J Nat) Cancer Inst 85:1129-1137, 1993]

AB - Background: Numerous studies have reported differences in cancer staging at diagnosis and in survival between Black and White patients with breast cancer. Utilizing data obtained from the National Cancer Institute's (NCI's) Black/White Cancer Survival Study for the period 1985-1986, a new study is presented here that systematically examines multiple explanatory factors (e.g., lack of mammograms) associated with these cancerstaging differences. Purpose: We evaluated within a single study the relationship of selected demographic, lifestyle, antecedent medical experiences, and health care access factors to cancer staging at diagnosis in Black and White breast cancer patients. Methods: Data utilized in this population-based cohort study of 1222 eligible women (649 Black and 573 White) newly diagnosed for the period 1985-1986 with histologically confirmed primary breast cancer were obtained from the NCI's Black/White Cancer Survival Study. Sources of data included abstracts of hospital medical records, central review of histology slides by a study consultant pathologist, and patient interviews obtained from three metropolitan areas: Atlanta, New Orleans, and San Francisco Oakland. Within each area, 70% of all Black incident cases were randomly selected, and a sample of White cases, frequency matched by age groups (20-49 years, 50-64 years, and 65-79 years), was selected for comparison. Stage of breast cancer at diagnosis was classified according to the international tumor-lymph nodemetastases (TNM) system. Statistical models utilized in this study included the log-linear and polychotomous logistic regression with multiple predictor variables. Results: Factors associated with cancer staging were differentially expressed in Blacks and Whites. Indicators of access to health care, a lack of mammograms, and an increased body mass index significantly (pNO cancer among Blacks compared with Whites (odds ratio reduction from 2.19 to 1.68). Conclusion: These findings suggest that no single factor or group of factors can explain more than half of the race-stage differences noted in this study with respect to Black and White breast cancer patients. [J Nat) Cancer Inst 85:1129-1137, 1993]

UR - http://www.scopus.com/inward/record.url?scp=0027327530&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027327530&partnerID=8YFLogxK

U2 - 10.1093/jnci/85.14.1129

DO - 10.1093/jnci/85.14.1129

M3 - Article

VL - 85

SP - 1129

EP - 1137

JO - Journal of the National Cancer Institute

JF - Journal of the National Cancer Institute

SN - 0027-8874

IS - 14

ER -