Breaking up receptor alliances: The parting of CD3 and CD4

A. Kupfer

Research output: Contribution to journalShort survey


The T-cell co-receptor CD4 is required for T-cell activation, and it may be involved in stabilization of the T-cell receptor and class II major histocompatibility complexes during antigen presentation. However, video microscopic analyses of the interactions between T cells and antigen-presenting cells indicate otherwise.

Original languageEnglish (US)
Pages (from-to)1097-1098
Number of pages2
JournalNature medicine
Issue number10
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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