Hirnstimulationsverfahren bei therapieresistenz

Translated title of the contribution: Brain stimulation methods for resistance to therapy

T. E. Schläpfer

Research output: Contribution to journalReview articlepeer-review


In psychiatry there is growing awareness of the urgent need for treatment of patients with severe depression who are refractory to treatment. While highly efficacious over its nearly 70-year history, electroconvulsive treatment is tainted with two basic disadvantages: high relapse quotas and sometimes extensive cognitive side effects. Therefore novel methods of brain stimulation are being employed: transcranial magnetic stimulation, magnetic seizure stimulation, vagus nerve stimulation, and deep brain stimulation. These four techniques are used in individual cases but still outside the framework of scientific research studies. Their clinical effects and effectivity require further definition. This paper reports the current status of brain stimulation methods and describes possible further developments.

Translated title of the contributionBrain stimulation methods for resistance to therapy
Original languageGerman
Pages (from-to)575-584
Number of pages10
Issue numberSUPPL. 3
StatePublished - Aug 2007
Externally publishedYes


  • Deep brain stimulation
  • Depression
  • Magnetic seizure therapy
  • Transcranial magnetic stimulation
  • Vagus nerve stimulation

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health


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