TY - JOUR
T1 - Brain-sparing total meningeal radiation for a patient with widespread progressive meningiomas using helical intensity modulated radiation
AU - Christodouleas, J. P.
AU - Latronico, D.
AU - Kleinberg, L.
PY - 2008/3
Y1 - 2008/3
N2 - Multiple meningioma is a rare but difficult clinical entity. We describe the case of a patient with widespread progressive meningiomas who could not safely have surgery or radiosurgery. We have previously treated these patients with whole brain radiation, despite the risks of neuropsychological side effects. In this case, we treated with a novel use of helical intensity modulated radiation therapy: brain-sparing total meningeal radiation. The brain-sparing technique allowed us to treat the patient's meninges with higher doses than would have been possible with whole brain radiation and with the goal of achieving long-term disease control.
AB - Multiple meningioma is a rare but difficult clinical entity. We describe the case of a patient with widespread progressive meningiomas who could not safely have surgery or radiosurgery. We have previously treated these patients with whole brain radiation, despite the risks of neuropsychological side effects. In this case, we treated with a novel use of helical intensity modulated radiation therapy: brain-sparing total meningeal radiation. The brain-sparing technique allowed us to treat the patient's meninges with higher doses than would have been possible with whole brain radiation and with the goal of achieving long-term disease control.
KW - Conformal radiotherapy
KW - Helical intensity modulated radiation therapy
KW - Multiple meningiomas
KW - Tomotherapy
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U2 - 10.1016/j.clineuro.2007.12.004
DO - 10.1016/j.clineuro.2007.12.004
M3 - Article
C2 - 18222034
AN - SCOPUS:39749083280
SN - 0303-8467
VL - 110
SP - 310
EP - 314
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
IS - 3
ER -