Brain morphometry and intelligence quotient measurements in children with sickle cell disease

Rong Chen, Mikolaj A. Pawlak, Thomas B. Flynn, Jaroslaw Krejza, Edward H. Herskovits, Elias R. Melhem

Research output: Contribution to journalArticle

Abstract

OBJECTIVE:: To verify the hypothesis that volume of regional gray matter accounts substantially for variability in intelligence quotient (IQ) score among children with sickle cell disease, who have no magnetic resonance visible infarcts. METHODS:: We studied 31 children with sickle cell disease, homozygous for hemoglobin S, with no history of stroke, no magnetic resonance signal-intensity abnormality, and transcranial Doppler velocities

Original languageEnglish (US)
Pages (from-to)509-517
Number of pages9
JournalJournal of Developmental and Behavioral Pediatrics
Volume30
Issue number6
DOIs
StatePublished - Dec 2009
Externally publishedYes

Fingerprint

Sickle Cell Anemia
Intelligence
Magnetic Resonance Spectroscopy
Sickle Hemoglobin
Brain
Stroke
Gray Matter

Keywords

  • Brain morphometry
  • Intelligence
  • Magnetic resonance
  • Psychological tests
  • Sickle cell disease

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology
  • Psychiatry and Mental health

Cite this

Brain morphometry and intelligence quotient measurements in children with sickle cell disease. / Chen, Rong; Pawlak, Mikolaj A.; Flynn, Thomas B.; Krejza, Jaroslaw; Herskovits, Edward H.; Melhem, Elias R.

In: Journal of Developmental and Behavioral Pediatrics, Vol. 30, No. 6, 12.2009, p. 509-517.

Research output: Contribution to journalArticle

Chen, Rong ; Pawlak, Mikolaj A. ; Flynn, Thomas B. ; Krejza, Jaroslaw ; Herskovits, Edward H. ; Melhem, Elias R. / Brain morphometry and intelligence quotient measurements in children with sickle cell disease. In: Journal of Developmental and Behavioral Pediatrics. 2009 ; Vol. 30, No. 6. pp. 509-517.
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