Abstract
PURPOSE: To compare directly the two most widely used methods of functional magnetic resonance (MR) imaging - dynamic contrast material-enhanced MR imaging and blood oxygenation level-dependent (BOLD) MR imaging. MATERIALS AND METHODS: Five healthy volunteers underwent dynamic contrast-enhanced and BOLD MR imaging with a conventional 1.5-T MR unit during visual stimulation and a dark control state. BOLD studies were performed with a gradient-echo sequence, and dynamic MR imaging was performed with an echo-shifted gradient-echo sequence after intravenous administration of a bolus of gadopentetate dimeglumine. RESULTS: A significantly greater percentage signal change was found with dynamic MR imaging than with the BOLD technique. The extent of area activated was also significantly greater. CONCLUSION: With standard clinical imagers and these gradient-echo-based techniques, greater percentage activation and area of activation can be achieved with dynamic MR imaging than with BOLD MR imaging.
Original language | English (US) |
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Pages (from-to) | 687-691 |
Number of pages | 5 |
Journal | RADIOLOGY |
Volume | 194 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1995 |
Externally published | Yes |
Keywords
- Blood, flow dynamics, 10.919
- Brain, MR, 17.121412, 17.121416, 17.12144
- Brain, function, 10.919
- Magnetic resonance (MR), rapid imaging
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging