Brain infarction in children with diabetic ketoacidosis

Thomas F. Roe; Thomas O. Crawford; Kenneth R. Huff; Gertrude Costin; Francine R. Kaufman; Marvin D. Nelson

doi:10.1016/1056-8727(94)00058-1

Brain infarction in children with diabetic ketoacidosis

Thomas F. Roe, Thomas O. Crawford, Kenneth R. Huff, Gertrude Costin, Francine R. Kaufman, Marvin D. Nelson

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

During the last 10 years, five children were treated at Childrens Hospital Los Angeles for acute, persistent neurologic loss during diabetic ketoacidosis (DKA). Four were transferred from local hospitals after the neurologic crisis. Computed tomography (CT) studies showed one or more areas of brain infarction in each patient, and none had evidence of diffuse cerebral edema. As three of the five patients had been treated for cerebral edema before their CT, brain edema may have been present initially. Our findings emphasize the importance of brain infarction as a cause of persistent neurologic loss in children with DKA.

Original language	English (US)
Pages (from-to)	100-108
Number of pages	9
Journal	Journal of Diabetes and its Complications
Volume	10
Issue number	2
DOIs	https://doi.org/10.1016/1056-8727(94)00058-1
State	Published - 1996
Externally published	Yes

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

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title = "Brain infarction in children with diabetic ketoacidosis",

abstract = "During the last 10 years, five children were treated at Childrens Hospital Los Angeles for acute, persistent neurologic loss during diabetic ketoacidosis (DKA). Four were transferred from local hospitals after the neurologic crisis. Computed tomography (CT) studies showed one or more areas of brain infarction in each patient, and none had evidence of diffuse cerebral edema. As three of the five patients had been treated for cerebral edema before their CT, brain edema may have been present initially. Our findings emphasize the importance of brain infarction as a cause of persistent neurologic loss in children with DKA.",

author = "Roe, {Thomas F.} and Crawford, {Thomas O.} and Huff, {Kenneth R.} and Gertrude Costin and Kaufman, {Francine R.} and Nelson, {Marvin D.}",

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AU - Crawford, Thomas O.

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AU - Costin, Gertrude

AU - Kaufman, Francine R.

AU - Nelson, Marvin D.

N1 - Funding Information: Supported by the Vikki Weiss Fund for Metabolic Research.

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Y1 - 1996

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AB - During the last 10 years, five children were treated at Childrens Hospital Los Angeles for acute, persistent neurologic loss during diabetic ketoacidosis (DKA). Four were transferred from local hospitals after the neurologic crisis. Computed tomography (CT) studies showed one or more areas of brain infarction in each patient, and none had evidence of diffuse cerebral edema. As three of the five patients had been treated for cerebral edema before their CT, brain edema may have been present initially. Our findings emphasize the importance of brain infarction as a cause of persistent neurologic loss in children with DKA.

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Brain infarction in children with diabetic ketoacidosis

Abstract

ASJC Scopus subject areas

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