Brain histamine: Rapid apparent turnover altered by restraint and cold stress

Kenneth M. Taylor; Solomon H. Snyder

doi:10.1126/science.172.3987.1037

Brain histamine: Rapid apparent turnover altered by restraint and cold stress

Kenneth M. Taylor, Solomon H. Snyder

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Histamine content of rat brain was lowered quickly by inhibitors of histidine decarboxylase, suggesting that a portion of brain histamine turns over rapidly. Restraint and exposure to cold also reduced brain histamine levels and markedly augmented its formation in the hypothalamus.

Original language	English (US)
Pages (from-to)	1037-1039
Number of pages	3
Journal	Science
Volume	172
Issue number	3987
DOIs	https://doi.org/10.1126/science.172.3987.1037
State	Published - Jan 1 1971

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title = "Brain histamine: Rapid apparent turnover altered by restraint and cold stress",

abstract = "Histamine content of rat brain was lowered quickly by inhibitors of histidine decarboxylase, suggesting that a portion of brain histamine turns over rapidly. Restraint and exposure to cold also reduced brain histamine levels and markedly augmented its formation in the hypothalamus.",

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Brain histamine: Rapid apparent turnover altered by restraint and cold stress

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