Abstract
Bovine papillomavirus type 1 (BPV-1) and type 2 (BPV-2) are the etiologic agents of fibropapillomas in cattle. Polyclonal antisera produced against BPV-1 structural antigens are cross-reactive with BPV-2. In this study BPV-1 type-specific monoclonal antibodies were produced that were not reactive with BPV-2. These monoclonal antibodies could be used for identification of BPV-1 structural antigens in acetone-fixed, frozen sections by immunofluorescence and Formalin-fixed, paraffin-embedded sections by immunoperoxidase techniques. In addition, these antibodies could be used for identification and purification of BPV-1 virions by immune electron microscopy and immunoadsorption techniques, respectively.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 121-125 |
| Number of pages | 5 |
| Journal | Journal of the National Cancer Institute |
| Volume | 75 |
| Issue number | 1 |
| State | Published - 1985 |
| Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Cancer Research