Border-cell migration: The race is on

Denise J. Montell

Research output: Contribution to journalArticle

Abstract

The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion.

Original languageEnglish (US)
Pages (from-to)13-24
Number of pages12
JournalNature Reviews Molecular Cell Biology
Volume4
Issue number1
DOIs
StatePublished - Jan 1 2003

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Cell Movement
Neoplasms
Drosophila melanogaster
Embryonic Development
Ovary
Epithelial Cells
Neoplasm Metastasis
Genes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Cite this

Border-cell migration : The race is on. / Montell, Denise J.

In: Nature Reviews Molecular Cell Biology, Vol. 4, No. 1, 01.01.2003, p. 13-24.

Research output: Contribution to journalArticle

Montell, Denise J. / Border-cell migration : The race is on. In: Nature Reviews Molecular Cell Biology. 2003 ; Vol. 4, No. 1. pp. 13-24.
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