TY - JOUR
T1 - Bone scintigraphic patterns in patients of tumor induced osteomalacia
AU - Sood, Ashwani
AU - Agarwal, Kanhaiyalal
AU - Shukla, Jaya
AU - Goel, Reema
AU - Dhir, Varun
AU - Bhattacharya, Anish
AU - Mittal, Bhagwant Rai
PY - 2013/7
Y1 - 2013/7
N2 - Tumor induced osteomalacia (TIO) or oncogenic osteomalacia is a rare condition associated with small tumor that secretes one of the phosphaturic hormones, i.e., fibroblast growth factor 23, resulting in abnormal phosphate metabolism. Patients may present with non-specific symptoms leading to delay in the diagnosis. Extensive skeletal involvement is frequently seen due to delay in the diagnosis and treatment. The small sized tumor and unexpected location make the identification of tumor difficult even after diagnosis of osteogenic osteomalacia. The bone scan done for the skeletal involvement may show the presence of metabolic features and the scan findings are a sensitive indicator of metabolic bone disorders. We present the bone scan findings in three patients diagnosed to have TIO.
AB - Tumor induced osteomalacia (TIO) or oncogenic osteomalacia is a rare condition associated with small tumor that secretes one of the phosphaturic hormones, i.e., fibroblast growth factor 23, resulting in abnormal phosphate metabolism. Patients may present with non-specific symptoms leading to delay in the diagnosis. Extensive skeletal involvement is frequently seen due to delay in the diagnosis and treatment. The small sized tumor and unexpected location make the identification of tumor difficult even after diagnosis of osteogenic osteomalacia. The bone scan done for the skeletal involvement may show the presence of metabolic features and the scan findings are a sensitive indicator of metabolic bone disorders. We present the bone scan findings in three patients diagnosed to have TIO.
KW - Bone scan
KW - Fibroblast growth factor 23
KW - Hypophosphatemia
KW - Tumor induced osteomalacia
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U2 - 10.4103/0972-3919.119541
DO - 10.4103/0972-3919.119541
M3 - Article
C2 - 24250028
AN - SCOPUS:84885975219
SN - 0972-3919
VL - 28
SP - 173
EP - 175
JO - Indian Journal of Nuclear Medicine
JF - Indian Journal of Nuclear Medicine
IS - 3
ER -