Bone scintigraphic patterns in patients of tumor induced osteomalacia

Ashwani Sood, Kanhaiyalal Agarwal, Jaya Shukla, Reema Goel, Varun Dhir, Anish Bhattacharya, Bhagwant Rai Mittal

Research output: Contribution to journalArticlepeer-review

Abstract

Tumor induced osteomalacia (TIO) or oncogenic osteomalacia is a rare condition associated with small tumor that secretes one of the phosphaturic hormones, i.e., fibroblast growth factor 23, resulting in abnormal phosphate metabolism. Patients may present with non-specific symptoms leading to delay in the diagnosis. Extensive skeletal involvement is frequently seen due to delay in the diagnosis and treatment. The small sized tumor and unexpected location make the identification of tumor difficult even after diagnosis of osteogenic osteomalacia. The bone scan done for the skeletal involvement may show the presence of metabolic features and the scan findings are a sensitive indicator of metabolic bone disorders. We present the bone scan findings in three patients diagnosed to have TIO.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalIndian Journal of Nuclear Medicine
Volume28
Issue number3
DOIs
StatePublished - Jul 2013
Externally publishedYes

Keywords

  • Bone scan
  • Fibroblast growth factor 23
  • Hypophosphatemia
  • Tumor induced osteomalacia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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