Abstract
Musculoskeletal disease is one of the most prevalent categories of pathology in the captive common marmoset. In this chapter, we will review the basic physiology of the musculoskeletal system, highlight the peculiarities of this system in marmosets, and discuss common methods for the diagnosis of musculoskeletal disease, including radiographic and biomarker assays. We will then specifically review the etiology, diagnosis, and treatment of common diseases of the musculoskeletal system in marmosets, including metabolic bone disease, and marmoset wasting syndrome, and discuss how marmosets have been used as translational animal models for osteoporosis, arthritis, and other musculoskeletal diseases.
Original language | English (US) |
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Title of host publication | The Common Marmoset in Captivity and Biomedical Research |
Publisher | Elsevier |
Pages | 231-250 |
Number of pages | 20 |
ISBN (Electronic) | 9780128118290 |
ISBN (Print) | 9780128118306 |
DOIs | |
State | Published - Jan 1 2018 |
Keywords
- Arthritis
- Fibrous osteodystrophy
- Marmoset wasting syndrome
- Osteopenia
- Osteoporosis
- Rickets
- Vitamin d
ASJC Scopus subject areas
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology