Bone mineral density in women with type II diabetes mellitus

R. S. Weinstock, R. S. Goland, E. Shane, Thomas Clemens, R. Lindsay, J. P. Bilezikian

Research output: Contribution to journalArticle

Abstract

Bone mineral density (BMD) was assessed in 28 women with type II diabetes mellitus and compared to 207 age-matched nondiabetic women. Mean BMD, as measured by dual-photon absorptiometry, 1.12 ± 0.3 g/cm2 (± SEM), was similar to the mean BMD of control subjects, 1.06 ± 0.1 g/cm2. Only 1 of the 28 diabetic patients had a BMD less than 0.95 g/cm2 ('fracture threshold'), whereas 25% of the control subjects had a BMD below that level. When diabetic and control subjects were matched for weight as well as age, the data continued to show similar BMD among both groups. Moreover, the disparity between the proportion of weight-matched controls (25%) and diabetic subjects (1 of 28) with a BMD below the fracture threshold persisted. Among the group of 17 diabetic subjects receiving insulin, there was a positive relationship between BMD and insulin dose. There was no significant relationship between BMD, duration of diabetes, or hemoglobin A(1c). Thus, women with type II diabetes are not at increased risk for diminished BMD and may be protected against bone loss.

Original languageEnglish (US)
Pages (from-to)97-101
Number of pages5
JournalJournal of Bone and Mineral Research
Volume4
Issue number1
StatePublished - 1989
Externally publishedYes

Fingerprint

Bone Density
Type 2 Diabetes Mellitus
Insulin
Hemoglobin A
Weights and Measures
Photon Absorptiometry
Bone and Bones

ASJC Scopus subject areas

  • Surgery

Cite this

Weinstock, R. S., Goland, R. S., Shane, E., Clemens, T., Lindsay, R., & Bilezikian, J. P. (1989). Bone mineral density in women with type II diabetes mellitus. Journal of Bone and Mineral Research, 4(1), 97-101.

Bone mineral density in women with type II diabetes mellitus. / Weinstock, R. S.; Goland, R. S.; Shane, E.; Clemens, Thomas; Lindsay, R.; Bilezikian, J. P.

In: Journal of Bone and Mineral Research, Vol. 4, No. 1, 1989, p. 97-101.

Research output: Contribution to journalArticle

Weinstock, RS, Goland, RS, Shane, E, Clemens, T, Lindsay, R & Bilezikian, JP 1989, 'Bone mineral density in women with type II diabetes mellitus', Journal of Bone and Mineral Research, vol. 4, no. 1, pp. 97-101.
Weinstock RS, Goland RS, Shane E, Clemens T, Lindsay R, Bilezikian JP. Bone mineral density in women with type II diabetes mellitus. Journal of Bone and Mineral Research. 1989;4(1):97-101.
Weinstock, R. S. ; Goland, R. S. ; Shane, E. ; Clemens, Thomas ; Lindsay, R. ; Bilezikian, J. P. / Bone mineral density in women with type II diabetes mellitus. In: Journal of Bone and Mineral Research. 1989 ; Vol. 4, No. 1. pp. 97-101.
@article{75ee765a549646ee98cd4576fd5513fb,
title = "Bone mineral density in women with type II diabetes mellitus",
abstract = "Bone mineral density (BMD) was assessed in 28 women with type II diabetes mellitus and compared to 207 age-matched nondiabetic women. Mean BMD, as measured by dual-photon absorptiometry, 1.12 ± 0.3 g/cm2 (± SEM), was similar to the mean BMD of control subjects, 1.06 ± 0.1 g/cm2. Only 1 of the 28 diabetic patients had a BMD less than 0.95 g/cm2 ('fracture threshold'), whereas 25{\%} of the control subjects had a BMD below that level. When diabetic and control subjects were matched for weight as well as age, the data continued to show similar BMD among both groups. Moreover, the disparity between the proportion of weight-matched controls (25{\%}) and diabetic subjects (1 of 28) with a BMD below the fracture threshold persisted. Among the group of 17 diabetic subjects receiving insulin, there was a positive relationship between BMD and insulin dose. There was no significant relationship between BMD, duration of diabetes, or hemoglobin A(1c). Thus, women with type II diabetes are not at increased risk for diminished BMD and may be protected against bone loss.",
author = "Weinstock, {R. S.} and Goland, {R. S.} and E. Shane and Thomas Clemens and R. Lindsay and Bilezikian, {J. P.}",
year = "1989",
language = "English (US)",
volume = "4",
pages = "97--101",
journal = "Journal of Bone and Mineral Research",
issn = "0884-0431",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Bone mineral density in women with type II diabetes mellitus

AU - Weinstock, R. S.

AU - Goland, R. S.

AU - Shane, E.

AU - Clemens, Thomas

AU - Lindsay, R.

AU - Bilezikian, J. P.

PY - 1989

Y1 - 1989

N2 - Bone mineral density (BMD) was assessed in 28 women with type II diabetes mellitus and compared to 207 age-matched nondiabetic women. Mean BMD, as measured by dual-photon absorptiometry, 1.12 ± 0.3 g/cm2 (± SEM), was similar to the mean BMD of control subjects, 1.06 ± 0.1 g/cm2. Only 1 of the 28 diabetic patients had a BMD less than 0.95 g/cm2 ('fracture threshold'), whereas 25% of the control subjects had a BMD below that level. When diabetic and control subjects were matched for weight as well as age, the data continued to show similar BMD among both groups. Moreover, the disparity between the proportion of weight-matched controls (25%) and diabetic subjects (1 of 28) with a BMD below the fracture threshold persisted. Among the group of 17 diabetic subjects receiving insulin, there was a positive relationship between BMD and insulin dose. There was no significant relationship between BMD, duration of diabetes, or hemoglobin A(1c). Thus, women with type II diabetes are not at increased risk for diminished BMD and may be protected against bone loss.

AB - Bone mineral density (BMD) was assessed in 28 women with type II diabetes mellitus and compared to 207 age-matched nondiabetic women. Mean BMD, as measured by dual-photon absorptiometry, 1.12 ± 0.3 g/cm2 (± SEM), was similar to the mean BMD of control subjects, 1.06 ± 0.1 g/cm2. Only 1 of the 28 diabetic patients had a BMD less than 0.95 g/cm2 ('fracture threshold'), whereas 25% of the control subjects had a BMD below that level. When diabetic and control subjects were matched for weight as well as age, the data continued to show similar BMD among both groups. Moreover, the disparity between the proportion of weight-matched controls (25%) and diabetic subjects (1 of 28) with a BMD below the fracture threshold persisted. Among the group of 17 diabetic subjects receiving insulin, there was a positive relationship between BMD and insulin dose. There was no significant relationship between BMD, duration of diabetes, or hemoglobin A(1c). Thus, women with type II diabetes are not at increased risk for diminished BMD and may be protected against bone loss.

UR - http://www.scopus.com/inward/record.url?scp=0024556630&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024556630&partnerID=8YFLogxK

M3 - Article

C2 - 2718784

AN - SCOPUS:0024556630

VL - 4

SP - 97

EP - 101

JO - Journal of Bone and Mineral Research

JF - Journal of Bone and Mineral Research

SN - 0884-0431

IS - 1

ER -