Bone Mineral Density and Cognitive Decline in Elderly Women: Results from the InCHIANTI Study

Alice Laudisio, Davide Onofrio Fontana, Chiara Rivera, Carmelinda Ruggiero, Stefania Bandinelli, Antonella Gemma, Luigi Ferrucci, Raffaele Antonelli Incalzi

Research output: Contribution to journalArticlepeer-review

Abstract

Osteoporosis and cognitive impairment, which are highly prevalent conditions in elderly populations, share several risk factors. This study aims at evaluating the association of bone mineral density (BMD) with prevalent and incident cognitive impairment after a 3-year follow-up. We studied 655 community-dwelling women aged 65+ participating in the InCHIANTI study, who had been followed for 3 years. Total, trabecular, and cortical BMD were estimated by peripheral quantitative computed tomography using standard transverse scans at 4 and 38 % of the tibial length. Cognitive performance was evaluated using the Mini-Mental State Examination and the Trail Making Tests (TMT) A and B; a MMSE score

Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalCalcified Tissue International
DOIs
StateAccepted/In press - Dec 28 2015
Externally publishedYes

Keywords

  • Bone mineral density
  • Cognitive performance
  • Elderly
  • Epidemiology

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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