Body mass index and incident ischemic heart disease in South Korean men and women

Sun Ha Jee; Roberto Pastor-Barriuso; Lawrence J. Appel; Il Sun; Edgar R. Miller; Eliseo Guallar

doi:10.1093/aje/kwi166

Body mass index and incident ischemic heart disease in South Korean men and women

Sun Ha Jee, Roberto Pastor-Barriuso, Lawrence J. Appel, Il Sun, Edgar R. Miller, Eliseo Guallar

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32 Scopus citations

Abstract

Asian populations have a higher body fat percentage for a given body mass index (BMI) than Caucasians. However, little information is available on the association of BMI with ischemic heart disease (IHD) incidence in Asians at low BMI levels. The authors prospectively evaluated the association of BMI (weight (kg)/height (m)²) with IHD incidence over 9 years of follow-up (1993-2001) among 133,740 South Korean adults (89,050 men, 44,690 women) who participated in the 1990 and 1992 examinations of the Korea Medical Insurance Corporation Study. Average BMI at baseline was 23.4 (standard deviation, 2.3) in men and 22.3 (standard deviation, 2.3) in women. After multivariate adjustment, there was a 14% (95% confidence interval: 12,16) increased risk of incident IHD per unit of increase in BMI. This trend was also observed within the range considered normal by Western standards, and a BMI of 24-<25 was associated with an IHD hazard ratio of 2.01 (95% confidence interval: 1.32, 3.05) in comparison with a BMI of 18-<19. The association of BMI with IHD in this cohort of relatively young South Korean men and women was progressive over the range of BMI values, with no threshold of change in risk and no indication of a U-shaped relation at low BMI levels.

Original language	English (US)
Pages (from-to)	42-48
Number of pages	7
Journal	American journal of epidemiology
Volume	162
Issue number	1
DOIs	https://doi.org/10.1093/aje/kwi166
State	Published - Jul 1 2005

Keywords

Asian continental ancestry group
Body mass index
Body weight
Myocardial ischemia
Obesity

ASJC Scopus subject areas

General Medicine

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10.1093/aje/kwi166

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title = "Body mass index and incident ischemic heart disease in South Korean men and women",

abstract = "Asian populations have a higher body fat percentage for a given body mass index (BMI) than Caucasians. However, little information is available on the association of BMI with ischemic heart disease (IHD) incidence in Asians at low BMI levels. The authors prospectively evaluated the association of BMI (weight (kg)/height (m)2) with IHD incidence over 9 years of follow-up (1993-2001) among 133,740 South Korean adults (89,050 men, 44,690 women) who participated in the 1990 and 1992 examinations of the Korea Medical Insurance Corporation Study. Average BMI at baseline was 23.4 (standard deviation, 2.3) in men and 22.3 (standard deviation, 2.3) in women. After multivariate adjustment, there was a 14% (95% confidence interval: 12,16) increased risk of incident IHD per unit of increase in BMI. This trend was also observed within the range considered normal by Western standards, and a BMI of 24-<25 was associated with an IHD hazard ratio of 2.01 (95% confidence interval: 1.32, 3.05) in comparison with a BMI of 18-<19. The association of BMI with IHD in this cohort of relatively young South Korean men and women was progressive over the range of BMI values, with no threshold of change in risk and no indication of a U-shaped relation at low BMI levels.",

keywords = "Asian continental ancestry group, Body mass index, Body weight, Myocardial ischemia, Obesity",

author = "Jee, {Sun Ha} and Roberto Pastor-Barriuso and Appel, {Lawrence J.} and Il Sun and Miller, {Edgar R.} and Eliseo Guallar",

note = "Funding Information: Dr. Roberto Pastor-Barriuso was supported in part by a grant from the Instituto de Salud Carlos III (EPY 1261/02). Conflict of interest: none declared.",

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AU - Pastor-Barriuso, Roberto

AU - Appel, Lawrence J.

AU - Sun, Il

AU - Miller, Edgar R.

AU - Guallar, Eliseo

N1 - Funding Information: Dr. Roberto Pastor-Barriuso was supported in part by a grant from the Instituto de Salud Carlos III (EPY 1261/02). Conflict of interest: none declared.

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N2 - Asian populations have a higher body fat percentage for a given body mass index (BMI) than Caucasians. However, little information is available on the association of BMI with ischemic heart disease (IHD) incidence in Asians at low BMI levels. The authors prospectively evaluated the association of BMI (weight (kg)/height (m)2) with IHD incidence over 9 years of follow-up (1993-2001) among 133,740 South Korean adults (89,050 men, 44,690 women) who participated in the 1990 and 1992 examinations of the Korea Medical Insurance Corporation Study. Average BMI at baseline was 23.4 (standard deviation, 2.3) in men and 22.3 (standard deviation, 2.3) in women. After multivariate adjustment, there was a 14% (95% confidence interval: 12,16) increased risk of incident IHD per unit of increase in BMI. This trend was also observed within the range considered normal by Western standards, and a BMI of 24-<25 was associated with an IHD hazard ratio of 2.01 (95% confidence interval: 1.32, 3.05) in comparison with a BMI of 18-<19. The association of BMI with IHD in this cohort of relatively young South Korean men and women was progressive over the range of BMI values, with no threshold of change in risk and no indication of a U-shaped relation at low BMI levels.

AB - Asian populations have a higher body fat percentage for a given body mass index (BMI) than Caucasians. However, little information is available on the association of BMI with ischemic heart disease (IHD) incidence in Asians at low BMI levels. The authors prospectively evaluated the association of BMI (weight (kg)/height (m)2) with IHD incidence over 9 years of follow-up (1993-2001) among 133,740 South Korean adults (89,050 men, 44,690 women) who participated in the 1990 and 1992 examinations of the Korea Medical Insurance Corporation Study. Average BMI at baseline was 23.4 (standard deviation, 2.3) in men and 22.3 (standard deviation, 2.3) in women. After multivariate adjustment, there was a 14% (95% confidence interval: 12,16) increased risk of incident IHD per unit of increase in BMI. This trend was also observed within the range considered normal by Western standards, and a BMI of 24-<25 was associated with an IHD hazard ratio of 2.01 (95% confidence interval: 1.32, 3.05) in comparison with a BMI of 18-<19. The association of BMI with IHD in this cohort of relatively young South Korean men and women was progressive over the range of BMI values, with no threshold of change in risk and no indication of a U-shaped relation at low BMI levels.

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Body mass index and incident ischemic heart disease in South Korean men and women

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