Blood glucose rise after lactose tolerance testing in infants

D. M. Paige, E. D. Mellits, F. Y. Chiu, L. Davis, T. M. Bayless, A. Cordano

Research output: Contribution to journalArticle


Lactose tolerance tests are used clinically to screen children and infants. It is assumed that absorption of a lactose challenge in infants would occur in a predictable pattern prior to weaning. Twenty-one infants from 3 to 12 months of age were studied. The maximum blood glucose rise over fasting levels ranged from 11.0 to 62.0 mg/100 ml; the mean was 32.6 mg/100 ml. Six infants had a maximum rise of less than 20 mg/100 ml. Eleven infants (52%) had a maximum rise of greater than 30 mg/100 ml. Signs of intolerance were not noted in any subject. Weight and length were normally distributed. Results indicate the variance in glucose rise existing within a population of infants growing normally and consuming milk. Gastric emptying, digestion, and absorption may influence the blood glucose rise after a lactose test. Established glucose levels used as an index to lactose absorption in older children and adults may not accurately reflect lactase activity in infants.

Original languageEnglish (US)
Pages (from-to)222-225
Number of pages4
JournalUnknown Journal
Issue number2
StatePublished - Jan 1 1978

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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