Blood glucose monitoring in symptomatic hypoglycemia

R. A. Cole, G. W. Benedict, Simeon Margolis, A. Kowarski

Research output: Contribution to journalArticle

Abstract

The relationship between blood glucose levels and the onset of hypoglycemic symptoms was studied by continuous monitoring of blood glucose levels after an oral glucose load in nine adults with normal glucose tolerance, five with chemical diabetes without symptomatic hypoglycemia, and nine with chemical diabetes with symptomatic hypoglycemia. Symptoms were associated not only with a low level of blood glucose but with a rapid fall as well. These two parameters were used to calculate a 'hypoglycemic index' (defined as the fall in blood glucose during a 90-minute period prior to reaching the minimum level, divided by the value of this minimum level). The hypoglycemic index was 2.3 ± 0.6 (mean ± S.D.) in the group of diabetic patients with symptomatic reactive hypoglycemia and 0.7 ± 0.3 for the other groups. This index may aid in the diagnosis of patients with symptoms of hypoglycemia and equivocally low values of blood glucose.

Original languageEnglish (US)
Pages (from-to)984-988
Number of pages5
JournalDiabetes
Volume25
Issue number10
StatePublished - 1976

Fingerprint

Hypoglycemia
Blood Glucose
Hypoglycemic Agents
Glucose

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Cole, R. A., Benedict, G. W., Margolis, S., & Kowarski, A. (1976). Blood glucose monitoring in symptomatic hypoglycemia. Diabetes, 25(10), 984-988.

Blood glucose monitoring in symptomatic hypoglycemia. / Cole, R. A.; Benedict, G. W.; Margolis, Simeon; Kowarski, A.

In: Diabetes, Vol. 25, No. 10, 1976, p. 984-988.

Research output: Contribution to journalArticle

Cole, RA, Benedict, GW, Margolis, S & Kowarski, A 1976, 'Blood glucose monitoring in symptomatic hypoglycemia', Diabetes, vol. 25, no. 10, pp. 984-988.
Cole RA, Benedict GW, Margolis S, Kowarski A. Blood glucose monitoring in symptomatic hypoglycemia. Diabetes. 1976;25(10):984-988.
Cole, R. A. ; Benedict, G. W. ; Margolis, Simeon ; Kowarski, A. / Blood glucose monitoring in symptomatic hypoglycemia. In: Diabetes. 1976 ; Vol. 25, No. 10. pp. 984-988.
@article{63154fc61e6e42b0abc3bac562b58160,
title = "Blood glucose monitoring in symptomatic hypoglycemia",
abstract = "The relationship between blood glucose levels and the onset of hypoglycemic symptoms was studied by continuous monitoring of blood glucose levels after an oral glucose load in nine adults with normal glucose tolerance, five with chemical diabetes without symptomatic hypoglycemia, and nine with chemical diabetes with symptomatic hypoglycemia. Symptoms were associated not only with a low level of blood glucose but with a rapid fall as well. These two parameters were used to calculate a 'hypoglycemic index' (defined as the fall in blood glucose during a 90-minute period prior to reaching the minimum level, divided by the value of this minimum level). The hypoglycemic index was 2.3 ± 0.6 (mean ± S.D.) in the group of diabetic patients with symptomatic reactive hypoglycemia and 0.7 ± 0.3 for the other groups. This index may aid in the diagnosis of patients with symptoms of hypoglycemia and equivocally low values of blood glucose.",
author = "Cole, {R. A.} and Benedict, {G. W.} and Simeon Margolis and A. Kowarski",
year = "1976",
language = "English (US)",
volume = "25",
pages = "984--988",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association Inc.",
number = "10",

}

TY - JOUR

T1 - Blood glucose monitoring in symptomatic hypoglycemia

AU - Cole, R. A.

AU - Benedict, G. W.

AU - Margolis, Simeon

AU - Kowarski, A.

PY - 1976

Y1 - 1976

N2 - The relationship between blood glucose levels and the onset of hypoglycemic symptoms was studied by continuous monitoring of blood glucose levels after an oral glucose load in nine adults with normal glucose tolerance, five with chemical diabetes without symptomatic hypoglycemia, and nine with chemical diabetes with symptomatic hypoglycemia. Symptoms were associated not only with a low level of blood glucose but with a rapid fall as well. These two parameters were used to calculate a 'hypoglycemic index' (defined as the fall in blood glucose during a 90-minute period prior to reaching the minimum level, divided by the value of this minimum level). The hypoglycemic index was 2.3 ± 0.6 (mean ± S.D.) in the group of diabetic patients with symptomatic reactive hypoglycemia and 0.7 ± 0.3 for the other groups. This index may aid in the diagnosis of patients with symptoms of hypoglycemia and equivocally low values of blood glucose.

AB - The relationship between blood glucose levels and the onset of hypoglycemic symptoms was studied by continuous monitoring of blood glucose levels after an oral glucose load in nine adults with normal glucose tolerance, five with chemical diabetes without symptomatic hypoglycemia, and nine with chemical diabetes with symptomatic hypoglycemia. Symptoms were associated not only with a low level of blood glucose but with a rapid fall as well. These two parameters were used to calculate a 'hypoglycemic index' (defined as the fall in blood glucose during a 90-minute period prior to reaching the minimum level, divided by the value of this minimum level). The hypoglycemic index was 2.3 ± 0.6 (mean ± S.D.) in the group of diabetic patients with symptomatic reactive hypoglycemia and 0.7 ± 0.3 for the other groups. This index may aid in the diagnosis of patients with symptoms of hypoglycemia and equivocally low values of blood glucose.

UR - http://www.scopus.com/inward/record.url?scp=0017045561&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017045561&partnerID=8YFLogxK

M3 - Article

C2 - 976608

AN - SCOPUS:0017045561

VL - 25

SP - 984

EP - 988

JO - Diabetes

JF - Diabetes

SN - 0012-1797

IS - 10

ER -