Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells

Judith R. Abrams, Susan L. Kelley, Elizabeth Hayes, Toyoko Kikuchi, Michael J. Brown, Sewon Kang, Mark G. Lebwohl, Cynthia A. Guzzo, Brian V. Jegasothy, Peter S. Linsley, James G. Krueger

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