Blink rates and receptor supersensitivity

Craig N. Karson; Richard A. Staub; Joel E. Kleinman; Richard Jed Wyatt

doi:10.1016/0028-3908(81)90049-6

Blink rates and receptor supersensitivity

Craig N. Karson, Richard A. Staub, Joel E. Kleinman, Richard Jed Wyatt

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

The dose response of blink rates to apomorphine was studied before and after holoperidol treatment in 4 monkeys. Seven days following holoperidol discontinuation there was no alteration of baseline blink rates but the blink rote response to low dose opomorphine was significantly increased indicating that haloperidol treatment had sensitized the animals.

Original language	English (US)
Pages (from-to)	91-93
Number of pages	3
Journal	Neuropharmacology
Volume	20
Issue number	1
DOIs	https://doi.org/10.1016/0028-3908(81)90049-6
State	Published - Jan 1981
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Cellular and Molecular Neuroscience

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10.1016/0028-3908(81)90049-6

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title = "Blink rates and receptor supersensitivity",

abstract = "The dose response of blink rates to apomorphine was studied before and after holoperidol treatment in 4 monkeys. Seven days following holoperidol discontinuation there was no alteration of baseline blink rates but the blink rote response to low dose opomorphine was significantly increased indicating that haloperidol treatment had sensitized the animals.",

author = "Karson, {Craig N.} and Staub, {Richard A.} and Kleinman, {Joel E.} and Wyatt, {Richard Jed}",

year = "1981",

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AU - Karson, Craig N.

AU - Staub, Richard A.

AU - Kleinman, Joel E.

AU - Wyatt, Richard Jed

PY - 1981/1

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N2 - The dose response of blink rates to apomorphine was studied before and after holoperidol treatment in 4 monkeys. Seven days following holoperidol discontinuation there was no alteration of baseline blink rates but the blink rote response to low dose opomorphine was significantly increased indicating that haloperidol treatment had sensitized the animals.

AB - The dose response of blink rates to apomorphine was studied before and after holoperidol treatment in 4 monkeys. Seven days following holoperidol discontinuation there was no alteration of baseline blink rates but the blink rote response to low dose opomorphine was significantly increased indicating that haloperidol treatment had sensitized the animals.

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M3 - Article

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JO - Neuropharmacology

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Blink rates and receptor supersensitivity

Abstract

ASJC Scopus subject areas

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