TY - JOUR
T1 - Bladder cancer in young women
AU - Piper, Joyce M.
AU - Matanoski, Genevieve M.
AU - Tonascia, James
N1 - Funding Information:
This project was supported by a National Research Service Traineeship Award (T32 CA 09314.03) from the US Public Health Service, Department of Health and Human Services. The authors thank the staff of the Cancer Registry of the New York State Department of Health for their assistance in this project. This paper is based on a thesis submitted by Joyce M. Piper to the Johns Hopkins University School of Hygiene and Public Health in partial fulfillment of the requirements for the Dr.P.H. degree.
PY - 1986/6
Y1 - 1986/6
N2 - The authors describe a population-based case-control study of cancer of the urinary bladder in New York State women aged 20-49 years (173 matched pairs) in 1975-1980. Both known and suspected risk factors for bladder cancer were examined for these rare, early-onset female cases. The odds ratio (OR) for cigarette smoking was 2.4 (95% confidence interval (Cl) = 1.5-4.0). Cases consumed more coffee per day than did controls (p <0.05). More cases than controls reported heavy use of drugs that contained phenacetin (OR = 6.5, 95% Cl = 1.5-59.2). In addition, more cases than controls reported that they had had a thyroid uptake procedure with radioactive iodine (iodine-131) (OR = 3.7, 95% Cl = 1.4-11.0). The odds ratios for these factors remained elevated after simultaneous adjustment with conditional logistic regression models. Consumption of artificial sweeteners, occupational history, bladder or kidney cancer in a first-degree relative, and a history of bladder infections were examined and found not to be risk factors for bladder cancer in this study.
AB - The authors describe a population-based case-control study of cancer of the urinary bladder in New York State women aged 20-49 years (173 matched pairs) in 1975-1980. Both known and suspected risk factors for bladder cancer were examined for these rare, early-onset female cases. The odds ratio (OR) for cigarette smoking was 2.4 (95% confidence interval (Cl) = 1.5-4.0). Cases consumed more coffee per day than did controls (p <0.05). More cases than controls reported heavy use of drugs that contained phenacetin (OR = 6.5, 95% Cl = 1.5-59.2). In addition, more cases than controls reported that they had had a thyroid uptake procedure with radioactive iodine (iodine-131) (OR = 3.7, 95% Cl = 1.4-11.0). The odds ratios for these factors remained elevated after simultaneous adjustment with conditional logistic regression models. Consumption of artificial sweeteners, occupational history, bladder or kidney cancer in a first-degree relative, and a history of bladder infections were examined and found not to be risk factors for bladder cancer in this study.
KW - Bladder neoplasms
KW - Iodine radioisotopes
KW - Phenacetin
KW - Smoking
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U2 - 10.1093/oxfordjournals.aje.a114331
DO - 10.1093/oxfordjournals.aje.a114331
M3 - Article
C2 - 3706274
AN - SCOPUS:0022458515
SN - 0002-9262
VL - 123
SP - 1033
EP - 1042
JO - American journal of epidemiology
JF - American journal of epidemiology
IS - 6
ER -