BK Viruria and Hemorrhagic Cystitis

Leopold G. Koss, Leo F. Verdonck, Adriaan W. Dekker, Maja Rozenberg-Arska, Jacoba G. Kapsenberg, Harrie G.a.m. Van de Avoort, Gijsbert C. de Gast, Ray R. Arthur, Keerti V. Shah, Rein Saral

Research output: Contribution to journalLetterpeer-review

2 Scopus citations


To the Editor: The conclusions of the paper by Arthur et al. (July 24 issue),1 ascribing hemorrhagic cystitis in recipients of bone marrow transplants to the activation of BK type human polyomavirus, may be interpreted differently. The virus forms characteristic intranuclear inclusions in urothelial cells that can be observed on routine microscopical cytologic examination of urinary sediment.2 Using this simple technique, we could document the presence of the virus in 12 of 3648 patients without evidence of severe disease, in 3 of 84 patients with diabetes mellitus, and in 5 of 37 patients with cancer who were receiving various forms…

Original languageEnglish (US)
Pages (from-to)108-109
Number of pages2
JournalNew England Journal of Medicine
Issue number2
StatePublished - Jan 8 1987

ASJC Scopus subject areas

  • Medicine(all)


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