Bizarre parosteal osteochondromatous proliferation: 16 Cases with a focus on histologic variability

Margaret Cocks, Elizabeth Helmke, Carolyn A. Meyers, Laura Fayad, Edward McCarthy, Aaron W. James

Research output: Contribution to journalArticlepeer-review

Abstract

Bizarre parosteal osteochondromatous proliferation (BPOP) is a benign bone and cartilage forming tumor occurring on the surface of bones, predominantly on the hands and feet. A defining feature of BPOP is the purplish-blue mineralization of cartilaginous tissue, known as ‘blue bone.’ Here, we report on an institutional series of 16 cases of BPOP, including radiographic, histologic, and histomorphometric features. All tumors were composed of some element of bone, cartilage, fibrous tissue and ‘blue bone,’ though the amount of each tissue sub-type varied widely. Some cases showed focal ‘blue bone’ only, however this was a defining feature in all cases.

Original languageEnglish (US)
Pages (from-to)138-142
Number of pages5
JournalJournal of Orthopaedics
Volume15
Issue number1
DOIs
StatePublished - Mar 2018

Keywords

  • BPOP
  • Bone tumor
  • Cartilage tumor
  • Osteochondroma
  • Surface bone tumor

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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