Bizarre parosteal osteochondromatous proliferation: 16 Cases with a focus on histologic variability

Margaret Cocks; Elizabeth Helmke; Carolyn A. Meyers; Laura Fayad; Edward McCarthy; Aaron W. James

doi:10.1016/j.jor.2018.01.028

Bizarre parosteal osteochondromatous proliferation: 16 Cases with a focus on histologic variability

Margaret Cocks, Elizabeth Helmke, Carolyn A. Meyers, Laura Fayad, Edward McCarthy, Aaron W. James

School of Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Bizarre parosteal osteochondromatous proliferation (BPOP) is a benign bone and cartilage forming tumor occurring on the surface of bones, predominantly on the hands and feet. A defining feature of BPOP is the purplish-blue mineralization of cartilaginous tissue, known as ‘blue bone.’ Here, we report on an institutional series of 16 cases of BPOP, including radiographic, histologic, and histomorphometric features. All tumors were composed of some element of bone, cartilage, fibrous tissue and ‘blue bone,’ though the amount of each tissue sub-type varied widely. Some cases showed focal ‘blue bone’ only, however this was a defining feature in all cases.

Original language	English (US)
Pages (from-to)	138-142
Number of pages	5
Journal	Journal of Orthopaedics
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.jor.2018.01.028
State	Published - Mar 2018

Keywords

BPOP
Bone tumor
Cartilage tumor
Osteochondroma
Surface bone tumor

ASJC Scopus subject areas

Orthopedics and Sports Medicine

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10.1016/j.jor.2018.01.028

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title = "Bizarre parosteal osteochondromatous proliferation: 16 Cases with a focus on histologic variability",

abstract = "Bizarre parosteal osteochondromatous proliferation (BPOP) is a benign bone and cartilage forming tumor occurring on the surface of bones, predominantly on the hands and feet. A defining feature of BPOP is the purplish-blue mineralization of cartilaginous tissue, known as {\textquoteleft}blue bone.{\textquoteright} Here, we report on an institutional series of 16 cases of BPOP, including radiographic, histologic, and histomorphometric features. All tumors were composed of some element of bone, cartilage, fibrous tissue and {\textquoteleft}blue bone,{\textquoteright} though the amount of each tissue sub-type varied widely. Some cases showed focal {\textquoteleft}blue bone{\textquoteright} only, however this was a defining feature in all cases.",

keywords = "BPOP, Bone tumor, Cartilage tumor, Osteochondroma, Surface bone tumor",

author = "Margaret Cocks and Elizabeth Helmke and Meyers, {Carolyn A.} and Laura Fayad and Edward McCarthy and James, {Aaron W.}",

note = "Funding Information: The present work was supported by the NIH/NIAMS ( K08 AR068316 ), the Musculoskeletal Transplant Foundation , the Orthopaedic Research and Education Foundation with funding provided by the Musculoskeletal Transplant Foundation , and Catherine and Constantinos J. Limas Research Award. Publisher Copyright: {\textcopyright} 2018",

year = "2018",

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doi = "10.1016/j.jor.2018.01.028",

language = "English (US)",

volume = "15",

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AU - Cocks, Margaret

AU - Helmke, Elizabeth

AU - Meyers, Carolyn A.

AU - Fayad, Laura

AU - McCarthy, Edward

AU - James, Aaron W.

N1 - Funding Information: The present work was supported by the NIH/NIAMS ( K08 AR068316 ), the Musculoskeletal Transplant Foundation , the Orthopaedic Research and Education Foundation with funding provided by the Musculoskeletal Transplant Foundation , and Catherine and Constantinos J. Limas Research Award. Publisher Copyright: © 2018

PY - 2018/3

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N2 - Bizarre parosteal osteochondromatous proliferation (BPOP) is a benign bone and cartilage forming tumor occurring on the surface of bones, predominantly on the hands and feet. A defining feature of BPOP is the purplish-blue mineralization of cartilaginous tissue, known as ‘blue bone.’ Here, we report on an institutional series of 16 cases of BPOP, including radiographic, histologic, and histomorphometric features. All tumors were composed of some element of bone, cartilage, fibrous tissue and ‘blue bone,’ though the amount of each tissue sub-type varied widely. Some cases showed focal ‘blue bone’ only, however this was a defining feature in all cases.

AB - Bizarre parosteal osteochondromatous proliferation (BPOP) is a benign bone and cartilage forming tumor occurring on the surface of bones, predominantly on the hands and feet. A defining feature of BPOP is the purplish-blue mineralization of cartilaginous tissue, known as ‘blue bone.’ Here, we report on an institutional series of 16 cases of BPOP, including radiographic, histologic, and histomorphometric features. All tumors were composed of some element of bone, cartilage, fibrous tissue and ‘blue bone,’ though the amount of each tissue sub-type varied widely. Some cases showed focal ‘blue bone’ only, however this was a defining feature in all cases.

KW - BPOP

KW - Bone tumor

KW - Cartilage tumor

KW - Osteochondroma

KW - Surface bone tumor

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Bizarre parosteal osteochondromatous proliferation: 16 Cases with a focus on histologic variability

Abstract

Keywords

ASJC Scopus subject areas

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