Bismuth triflate-catalyzed condensation of indoles with acetone

Ganesh M. Shelke, V. Kameshwara Rao, Rakesh K. Tiwari, Bhupender S. Chhikara, Keykavous Parang, Anil Kumar

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Reaction of different substituted indoles with acetone was investigated using Bi(OTf)3 as a catalyst. An efficient protocol was developed for the synthesis of spiro indoles, 1-methyl-cyclopenta[b]indole and bis(1-methyl-1H-indolyl)propanes via the reaction of indole with acetone in the presence of Bi(OTf)3. The reaction conditions were benign, required shorter reaction time, and gave good yields.

Original languageEnglish (US)
Pages (from-to)22346-22352
Number of pages7
JournalRSC Advances
Issue number44
StatePublished - 2013
Externally publishedYes

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Chemistry(all)


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