Bismuth in Infants with Watery Diarrhea

Jon S. Abramson, Laurence B. Givner, Charles R. Woods, Ernesto Guiraldes, Eduardo Salazar-Lindo, R. Bradley Sack, Dante Figueroa-Quintanilla

Research output: Contribution to journalLetter


To the Editor: Figueroa-Quintanilla et al. (June 10 issue)1 state that bismuth subsalicylate could be a useful, safe, and cost-effective adjunct to oral rehydration and nutritional therapy in children with acute watery diarrhea. We are surprised that they did not consider the risk of Reye's syndrome, since the use of aspirin, a salicylate-containing drug, has been associated with an increased risk of this syndrome. Whether or not there is an increased risk of Reye's syndrome with the use of bismuth subsalicylate remains to be determined. The syndrome, however, has been reported in patients whose only exposure to salicylates was to…

Original languageEnglish (US)
Pages (from-to)1742-1743
Number of pages2
JournalNew England Journal of Medicine
Issue number23
StatePublished - Dec 2 1993

ASJC Scopus subject areas

  • Medicine(all)

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    Abramson, J. S., Givner, L. B., Woods, C. R., Guiraldes, E., Salazar-Lindo, E., Sack, R. B., & Figueroa-Quintanilla, D. (1993). Bismuth in Infants with Watery Diarrhea. New England Journal of Medicine, 329(23), 1742-1743.