TY - JOUR
T1 - Bismuth in Infants with Watery Diarrhea
AU - Abramson, Jon S.
AU - Givner, Laurence B.
AU - Woods, Charles R.
AU - Guiraldes, Ernesto
AU - Salazar-Lindo, Eduardo
AU - Sack, R. Bradley
AU - Figueroa-Quintanilla, Dante
PY - 1993/12/2
Y1 - 1993/12/2
N2 - To the Editor: Figueroa-Quintanilla et al. (June 10 issue)1 state that bismuth subsalicylate could be a useful, safe, and cost-effective adjunct to oral rehydration and nutritional therapy in children with acute watery diarrhea. We are surprised that they did not consider the risk of Reye's syndrome, since the use of aspirin, a salicylate-containing drug, has been associated with an increased risk of this syndrome. Whether or not there is an increased risk of Reye's syndrome with the use of bismuth subsalicylate remains to be determined. The syndrome, however, has been reported in patients whose only exposure to salicylates was to…
AB - To the Editor: Figueroa-Quintanilla et al. (June 10 issue)1 state that bismuth subsalicylate could be a useful, safe, and cost-effective adjunct to oral rehydration and nutritional therapy in children with acute watery diarrhea. We are surprised that they did not consider the risk of Reye's syndrome, since the use of aspirin, a salicylate-containing drug, has been associated with an increased risk of this syndrome. Whether or not there is an increased risk of Reye's syndrome with the use of bismuth subsalicylate remains to be determined. The syndrome, however, has been reported in patients whose only exposure to salicylates was to…
UR - http://www.scopus.com/inward/record.url?scp=0027437979&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027437979&partnerID=8YFLogxK
U2 - 10.1056/NEJM199312023292319
DO - 10.1056/NEJM199312023292319
M3 - Letter
C2 - 8232479
AN - SCOPUS:0027437979
SN - 0028-4793
VL - 329
SP - 1742
EP - 1743
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 23
ER -