Bipolar radiofrequency ablation using internally cooled electrodes in ex vivo bovine liver: Prediction of coagulation volume from applied energy

Stephan Clasen, Diethard Schmidt, Klaus Dietz, Andreas Boss, Stefan M. Kröber, Christina Schraml, Jan Fritz, Claus D. Claussen, Philippe L. Pereira

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: We sought to evaluate the relationship between parameters of bipolar radiofrequency (RF) ablation using internally cooled electrodes. MATERIALS AND METHODS: Bipolar RF ablations (n = 24) were performed in ex vivo bovine liver using an internally cooled applicator with 2 electrodes located on the same shaft. The power-output was systematically varied (20-75 W). On the basis of our experimental data, mathematical functions were fitted and the goodness-of-fit was assessed by the parameter R. RESULTS: The duration to induce an increase of tissue resistance and the amount of applied energy increased with a decreased power-output. The maximum short-axis was 4.5 cm (20 W) and required an application of 64 kilojoules (kJ). The volume of coagulation can be determined as a function of the duration of energy application (R = 0.954) and the amount of applied energy (R = 0.945). CONCLUSION: The amount of applied energy and the duration of energy application can predict the volume of induced coagulation and may be useful to control internally cooled bipolar RF ablation.

Original languageEnglish (US)
Pages (from-to)29-36
Number of pages8
JournalInvestigative radiology
Volume42
Issue number1
DOIs
StatePublished - Jan 1 2007
Externally publishedYes

Keywords

  • Bipolar
  • Energy
  • Liver
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Bipolar radiofrequency ablation using internally cooled electrodes in ex vivo bovine liver: Prediction of coagulation volume from applied energy'. Together they form a unique fingerprint.

Cite this