Biphasic shocks induce more uniform repolarization than monophasic shocks in a cardiac cellular field excitation model

Eric A. Sobie, Matthew G. Fishler, Leslie Tung

Research output: Contribution to journalConference articlepeer-review

Abstract

A model of an isolated cardiac cell in a uniform electric field was used to study the differences in action potential prolongation produced by monophasic and biphasic field stimulation. Repolarization times induced by shocks of varying strengths delivered at different times in the relative refractory period were measured. Monophasic shocks were found to produce greater average prolongation, but the standard deviation of the biphasic repolarization times was less. The more uniform response caused by the biphasic pulse may help to explain the greater efficacy of biphasic waveforms in defibrillation.

Original languageEnglish (US)
Pages (from-to)257-258
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume17
Issue number1
StatePublished - Dec 1 1995
EventProceedings of the 1995 IEEE Engineering in Medicine and Biology 17th Annual Conference and 21st Canadian Medical and Biological Engineering Conference. Part 2 (of 2) - Montreal, Can
Duration: Sep 20 1995Sep 23 1995

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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