Biosynthesis of vitamin B12: Does 51-norcobyrinic acid or 151-norcobyrinic acid act as a precursor of cobyrinic acid?

Ingeborg Grgurina, Sheetal Handa, George Weaver, Philip A. Cole, Alan R. Battersby

Research output: Contribution to journalArticlepeer-review


51-Norcobyrinic acid and 151-norcobyrinic acid are prepared in labelled form for enzymic experiments that show that neither one acts as a biosynthetic precursor of cobyrinic acid, a late intermediate en route to vitamin B12.

Original languageEnglish (US)
Pages (from-to)1514-1516
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number21
StatePublished - Dec 1 1990

ASJC Scopus subject areas

  • Molecular Medicine


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