Biospecimen reporting for improved study quality (BRISQ)

Helen M. Moore, Andrea B. Kelly, Scott D. Jewell, Lisa M. McShane, Douglas P. Clark, Renata Greenspan, Daniel F. Hayes, Pierre Hainaut, Paula Kim, Elizabeth A. Mansfield, Olga Potapova, Peter Riegman, Yaffa Rubinstein, Edward Seijo, Stella Somiari, Peter Watson, Heinz Ulrich Weier, Claire Zhu, Jim Vaught

Research output: Contribution to journalArticle

Abstract

Human biospecimens are subjected to collection, processing, and storage that can significantly alter their molecular composition and consistency. These biospecimen preanalytical factors, in turn, influence experimental outcomes and the ability to reproduce scientific results. Currently, the extent and type of information specific to the biospecimen preanalytical conditions reported in scientific publications and regulatory submissions varies widely. To improve the quality of research that uses human tissues, it is crucial that information on the handling of biospecimens be reported in a thorough, accurate, and standardized manner. The Biospecimen Reporting for Improved Study Quality (BRISQ) recommendations outlined herein are intended to apply to any study in which human biospecimens are used. The purpose of reporting these details is to supply others, from researchers to regulators, with more consistent and standardized information to better evaluate, interpret, compare, and reproduce the experimental results. The BRISQ guidelines are proposed as an important and timely resource tool to strengthen communication and publications on biospecimen-related research and to help reassure patient contributors and the advocacy community that their contributions are valued and respected.

Original languageEnglish (US)
Pages (from-to)92-102
Number of pages11
JournalCancer Cytopathology
Volume119
Issue number2
DOIs
StatePublished - Apr 25 2011

Keywords

  • BRISQ
  • Best practices
  • Biobank
  • Biospecimen
  • Guidelines
  • Human
  • Quality
  • Research

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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  • Cite this

    Moore, H. M., Kelly, A. B., Jewell, S. D., McShane, L. M., Clark, D. P., Greenspan, R., Hayes, D. F., Hainaut, P., Kim, P., Mansfield, E. A., Potapova, O., Riegman, P., Rubinstein, Y., Seijo, E., Somiari, S., Watson, P., Weier, H. U., Zhu, C., & Vaught, J. (2011). Biospecimen reporting for improved study quality (BRISQ). Cancer Cytopathology, 119(2), 92-102. https://doi.org/10.1002/cncy.20147