Biomimetic particles as therapeutics

Randall A. Meyer, Joel C. Sunshine, Jordan Green

Research output: Contribution to journalArticle

Abstract

In recent years, there have been major advances in the development of novel nanoparticle- and microparticle-based therapeutics. An emerging paradigm is the incorporation of biomimetic features into these synthetic therapeutic constructs to enable them to better interface with biological systems. Through the control of size, shape, and material consistency, particle cores have been generated that better mimic natural cells and viruses. In addition, there have been significant advances in biomimetic surface functionalization of particles through the integration of bio-inspired artificial cell membranes and naturally derived cell membranes. Biomimetic technologies enable therapeutic particles to have increased potency to benefit human health.

Original languageEnglish (US)
JournalTrends in Biotechnology
Volume33
Issue number9
DOIs
StatePublished - Sep 1 2015

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Biomimetics
Cell membranes
Cell Membrane
Artificial Cells
Artificial Membranes
Insurance Benefits
Biological systems
Viruses
Nanoparticles
Therapeutics
Health
Technology

Keywords

  • Biomaterial
  • Biomimetic
  • Drug delivery
  • Micro/nanoparticle

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

Cite this

Biomimetic particles as therapeutics. / Meyer, Randall A.; Sunshine, Joel C.; Green, Jordan.

In: Trends in Biotechnology, Vol. 33, No. 9, 01.09.2015.

Research output: Contribution to journalArticle

Meyer, Randall A. ; Sunshine, Joel C. ; Green, Jordan. / Biomimetic particles as therapeutics. In: Trends in Biotechnology. 2015 ; Vol. 33, No. 9.
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