Biomechanics of nested transforaminal lumbar interbody cages

Hector Soriano-Baron, Anna G.U.S. Newcomb, Devika Malhotra, Kaylee De Tranaltes, Eduardo Martinez-Del-Campo, Phillip M. Reyes, Neil R. Crawford, Nicholas Theodore, Luis M. Tumialán

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Arthrodesis is optimized when the structural graft occupies most of the surface area within a disc space. The transforaminal corridor inherently limits interbody size. OBJECTIVE: To evaluate the biomechanical implications of nested interbody spacers (ie, a second curved cage placed behind a first) to increase disc space coverage in transforaminal approaches. METHODS: Seven lumbar human cadaveric specimens (L3-S1) underwent nondestructive flexibility and axial compression testing intact and after transforaminal instrumentation at L4-L5. Specimens were tested in 5 conditions: (1) intact, (2) interbody, (3) interbody plus bilateral pedicle screws and rods (PSR), (4) 2 nested interbodies, and (5) 2 nested interbodies plus PSR. RESULTS: Mean range of motion (ROM) with 1 interbody vs 2 nested interbodies, respectively, was: flexion, 101% vs 85%; extension, 97% vs 92%; lateral bending, 127% vs 132%; and axial rotation, 145% vs 154%. One interbody and 2 nested interbodies did not differ significantly by loading mode (P < .10). With PSR, ROM decreased significantly compared with intact, but not between interbody and interbody plus PSR or 2 interbodies plus PSR (P < .80). Mean vertical height during compressive loading (ie, axial compressive stiffness) was significantly different with 2 nested interbodies vs 1 interbody alone (P > .001) (compressive stiffness, 89% of intact vs 67% of intact, respectively). CONCLUSION: Inserting a second interbody using a transforaminal approach is anatomically feasible and nearly doubles the disc space covered without affecting ROM. Compressive stiffness significantly increased with 2 nested interbodies, and foraminal height increased. Evaluation of the clinical safety and efficacy of nested interbodies is underway.

Original languageEnglish (US)
Pages (from-to)297-303
Number of pages7
JournalNeurosurgery
Volume78
Issue number2
DOIs
StatePublished - Feb 1 2016
Externally publishedYes

Keywords

  • Cage
  • Lumbar
  • Nested
  • Transforaminal lumbar interbody fusion

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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