TY - JOUR
T1 - Biomechanics of nested transforaminal lumbar interbody cages
AU - Soriano-Baron, Hector
AU - Newcomb, Anna G.U.S.
AU - Malhotra, Devika
AU - De Tranaltes, Kaylee
AU - Martinez-Del-Campo, Eduardo
AU - Reyes, Phillip M.
AU - Crawford, Neil R.
AU - Theodore, Nicholas
AU - Tumialán, Luis M.
N1 - Publisher Copyright:
Copyright © 2015 by the Congress of Neurological Surgeons.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - BACKGROUND: Arthrodesis is optimized when the structural graft occupies most of the surface area within a disc space. The transforaminal corridor inherently limits interbody size. OBJECTIVE: To evaluate the biomechanical implications of nested interbody spacers (ie, a second curved cage placed behind a first) to increase disc space coverage in transforaminal approaches. METHODS: Seven lumbar human cadaveric specimens (L3-S1) underwent nondestructive flexibility and axial compression testing intact and after transforaminal instrumentation at L4-L5. Specimens were tested in 5 conditions: (1) intact, (2) interbody, (3) interbody plus bilateral pedicle screws and rods (PSR), (4) 2 nested interbodies, and (5) 2 nested interbodies plus PSR. RESULTS: Mean range of motion (ROM) with 1 interbody vs 2 nested interbodies, respectively, was: flexion, 101% vs 85%; extension, 97% vs 92%; lateral bending, 127% vs 132%; and axial rotation, 145% vs 154%. One interbody and 2 nested interbodies did not differ significantly by loading mode (P < .10). With PSR, ROM decreased significantly compared with intact, but not between interbody and interbody plus PSR or 2 interbodies plus PSR (P < .80). Mean vertical height during compressive loading (ie, axial compressive stiffness) was significantly different with 2 nested interbodies vs 1 interbody alone (P > .001) (compressive stiffness, 89% of intact vs 67% of intact, respectively). CONCLUSION: Inserting a second interbody using a transforaminal approach is anatomically feasible and nearly doubles the disc space covered without affecting ROM. Compressive stiffness significantly increased with 2 nested interbodies, and foraminal height increased. Evaluation of the clinical safety and efficacy of nested interbodies is underway.
AB - BACKGROUND: Arthrodesis is optimized when the structural graft occupies most of the surface area within a disc space. The transforaminal corridor inherently limits interbody size. OBJECTIVE: To evaluate the biomechanical implications of nested interbody spacers (ie, a second curved cage placed behind a first) to increase disc space coverage in transforaminal approaches. METHODS: Seven lumbar human cadaveric specimens (L3-S1) underwent nondestructive flexibility and axial compression testing intact and after transforaminal instrumentation at L4-L5. Specimens were tested in 5 conditions: (1) intact, (2) interbody, (3) interbody plus bilateral pedicle screws and rods (PSR), (4) 2 nested interbodies, and (5) 2 nested interbodies plus PSR. RESULTS: Mean range of motion (ROM) with 1 interbody vs 2 nested interbodies, respectively, was: flexion, 101% vs 85%; extension, 97% vs 92%; lateral bending, 127% vs 132%; and axial rotation, 145% vs 154%. One interbody and 2 nested interbodies did not differ significantly by loading mode (P < .10). With PSR, ROM decreased significantly compared with intact, but not between interbody and interbody plus PSR or 2 interbodies plus PSR (P < .80). Mean vertical height during compressive loading (ie, axial compressive stiffness) was significantly different with 2 nested interbodies vs 1 interbody alone (P > .001) (compressive stiffness, 89% of intact vs 67% of intact, respectively). CONCLUSION: Inserting a second interbody using a transforaminal approach is anatomically feasible and nearly doubles the disc space covered without affecting ROM. Compressive stiffness significantly increased with 2 nested interbodies, and foraminal height increased. Evaluation of the clinical safety and efficacy of nested interbodies is underway.
KW - Cage
KW - Lumbar
KW - Nested
KW - Transforaminal lumbar interbody fusion
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U2 - 10.1227/NEU.0000000000001005
DO - 10.1227/NEU.0000000000001005
M3 - Article
C2 - 26348015
AN - SCOPUS:84955326016
SN - 0148-396X
VL - 78
SP - 297
EP - 303
JO - Neurosurgery
JF - Neurosurgery
IS - 2
ER -