TY - JOUR
T1 - Biomechanical Strength of Rotator Cuff Repairs
T2 - A Systematic Review and Meta-regression Analysis of Cadaveric Studies
AU - Shi, Brendan Y.
AU - Diaz, Miguel
AU - Binkley, Matthew
AU - McFarland, Edward G.
AU - Srikumaran, Uma
N1 - Publisher Copyright:
© 2018 The Author(s).
PY - 2019/7/1
Y1 - 2019/7/1
N2 - Background: Biomechanical cadaveric studies of rotator cuff repair (RCR) have shown that transosseous equivalent and double-row anchored repairs are stronger than other repair constructs. Purpose: To identify technical and procedural parameters that most reliably predict biomechanical performance of RCR constructs. Study Design: Systematic review. Methods: The authors systematically searched the EMBASE and PubMed databases for biomechanical studies that measured RCR performance in cadaveric specimens. The authors performed a meta-regression on the pooled data set with study outcomes (gap formation, failure mode, and ultimate failure load) as dependent variables and procedural parameters (eg, construct type, number of suture limbs) as covariates. Stratification by covariates was performed. An alpha level of.05 was used. Results: Data from 40 eligible studies were included. Higher number of suture limbs correlated with higher ultimate failure load (β = 38 N per limb; 95% CI, 28 to 49 N) and less gap formation (β = −0.6 mm per limb; 95% CI, −1 to −0.2 mm). Other positive predictors of ultimate failure load were number of sutures, number of mattress stitches, and use of wide suture versus standard suture. When controlling for number of suture limbs, we found no significant differences among single-row anchored, double-row anchored, transosseous equivalent, and transosseous repairs. Higher number of suture limbs and transosseous equivalent repair both increased the probability of catastrophic construct failure. Conclusion: This study suggests that the number of sutures, suture limbs, and mattress stitches in a RCR construct are stronger predictors of overall strength than is construct type. There is a need to balance increased construct strength with higher risk of type 2 failure.
AB - Background: Biomechanical cadaveric studies of rotator cuff repair (RCR) have shown that transosseous equivalent and double-row anchored repairs are stronger than other repair constructs. Purpose: To identify technical and procedural parameters that most reliably predict biomechanical performance of RCR constructs. Study Design: Systematic review. Methods: The authors systematically searched the EMBASE and PubMed databases for biomechanical studies that measured RCR performance in cadaveric specimens. The authors performed a meta-regression on the pooled data set with study outcomes (gap formation, failure mode, and ultimate failure load) as dependent variables and procedural parameters (eg, construct type, number of suture limbs) as covariates. Stratification by covariates was performed. An alpha level of.05 was used. Results: Data from 40 eligible studies were included. Higher number of suture limbs correlated with higher ultimate failure load (β = 38 N per limb; 95% CI, 28 to 49 N) and less gap formation (β = −0.6 mm per limb; 95% CI, −1 to −0.2 mm). Other positive predictors of ultimate failure load were number of sutures, number of mattress stitches, and use of wide suture versus standard suture. When controlling for number of suture limbs, we found no significant differences among single-row anchored, double-row anchored, transosseous equivalent, and transosseous repairs. Higher number of suture limbs and transosseous equivalent repair both increased the probability of catastrophic construct failure. Conclusion: This study suggests that the number of sutures, suture limbs, and mattress stitches in a RCR construct are stronger predictors of overall strength than is construct type. There is a need to balance increased construct strength with higher risk of type 2 failure.
KW - meta-regression
KW - rotator cuff repair
KW - suture
KW - transosseous anchors
KW - transosseous equivalent
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U2 - 10.1177/0363546518780928
DO - 10.1177/0363546518780928
M3 - Review article
C2 - 29975549
AN - SCOPUS:85049832597
SN - 0363-5465
VL - 47
SP - 1984
EP - 1993
JO - American Journal of Sports Medicine
JF - American Journal of Sports Medicine
IS - 8
ER -