Biomarkers of secondhand smoke exposure in waterpipe tobacco venue employees in Istanbul, Moscow, and Cairo

Katherine A. Moon, Ana M Rule, Hoda S. Magid, Jacqueline M. Ferguson, Jolie Susan, Zhuolu Sun, Christine Torrey, Salahaddin Abubaker, Vladimir Levshin, Asli Çarkoglu, Ghada Nasr Radwan, Maha El-Rabbat, Joanna E Cohen, Paul Timothy Strickland, Patrick N Breysse, Ana Navas Acien

Research output: Contribution to journalArticle

Abstract

Background: Most smoke-free legislation to reduce secondhand smoke (SHS) exposure exempts waterpipe (hookah) smoking venues. Few studies have examined SHS exposure in waterpipe venues and their employees. Methods: We surveyed 276 employees of 46 waterpipe tobacco venues in Istanbul, Moscow, and Cairo. We interviewed venue managers and employees and collected biological samples from employees to measure exhaled carbon monoxide (CO), hair nicotine, saliva cotinine, urine cotinine, urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and urine 1-hydroxypyrene glucuronide (1-OHPG). We estimated adjusted geometric mean ratios (GMR) of each SHS biomarker by employee characteristics and indoor air SHS measures. Results: There were 73 nonsmoking employees and 203 current smokers of cigarettes or waterpipe. In nonsmokers, the median (interquartile) range concentrations of SHS biomarkers were 1.1 (0.2, 40.9) μg/g creatinine urine cotinine, 5.5 (2, 15) ng/mL saliva cotinine, 0.95 (0.36, 5.02) ng/mg hair nicotine, 1.48 (0.98, 3.97) pg/mg creatinine urine NNAL, 0.54 (0.25, 0.97) pmol/mg creatinine urine 1-OHPG, and 1.67 (1.33, 2.33) ppm exhaled CO. An 8-hour increase in work hours was associated with higher urine cotinine (GMR: 1.68, 95% CI: 1.20, 2.37) and hair nicotine (GMR: 1.22, 95% CI: 1.05, 1.43). Lighting waterpipes was associated with higher saliva cotinine (GMR: 2.83, 95% CI: 1.05, 7.62).

Original languageEnglish (US)
Pages (from-to)482-491
Number of pages10
JournalNicotine and Tobacco Research
Volume20
Issue number4
DOIs
StatePublished - Mar 6 2018

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Moscow
Tobacco Smoke Pollution
Cotinine
Tobacco
Biomarkers
Urine
Nicotine
Saliva
Hair
Creatinine
Carbon Monoxide
Smoking
Lighting
Legislation
Smoke
Tobacco Products
Air

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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Biomarkers of secondhand smoke exposure in waterpipe tobacco venue employees in Istanbul, Moscow, and Cairo. / Moon, Katherine A.; Rule, Ana M; Magid, Hoda S.; Ferguson, Jacqueline M.; Susan, Jolie; Sun, Zhuolu; Torrey, Christine; Abubaker, Salahaddin; Levshin, Vladimir; Çarkoglu, Asli; Radwan, Ghada Nasr; El-Rabbat, Maha; Cohen, Joanna E; Strickland, Paul Timothy; Breysse, Patrick N; Navas Acien, Ana.

In: Nicotine and Tobacco Research, Vol. 20, No. 4, 06.03.2018, p. 482-491.

Research output: Contribution to journalArticle

Moon, KA, Rule, AM, Magid, HS, Ferguson, JM, Susan, J, Sun, Z, Torrey, C, Abubaker, S, Levshin, V, Çarkoglu, A, Radwan, GN, El-Rabbat, M, Cohen, JE, Strickland, PT, Breysse, PN & Navas Acien, A 2018, 'Biomarkers of secondhand smoke exposure in waterpipe tobacco venue employees in Istanbul, Moscow, and Cairo', Nicotine and Tobacco Research, vol. 20, no. 4, pp. 482-491. https://doi.org/10.1093/ntr/ntx125
Moon, Katherine A. ; Rule, Ana M ; Magid, Hoda S. ; Ferguson, Jacqueline M. ; Susan, Jolie ; Sun, Zhuolu ; Torrey, Christine ; Abubaker, Salahaddin ; Levshin, Vladimir ; Çarkoglu, Asli ; Radwan, Ghada Nasr ; El-Rabbat, Maha ; Cohen, Joanna E ; Strickland, Paul Timothy ; Breysse, Patrick N ; Navas Acien, Ana. / Biomarkers of secondhand smoke exposure in waterpipe tobacco venue employees in Istanbul, Moscow, and Cairo. In: Nicotine and Tobacco Research. 2018 ; Vol. 20, No. 4. pp. 482-491.
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AU - Moon, Katherine A.

AU - Rule, Ana M

AU - Magid, Hoda S.

AU - Ferguson, Jacqueline M.

AU - Susan, Jolie

AU - Sun, Zhuolu

AU - Torrey, Christine

AU - Abubaker, Salahaddin

AU - Levshin, Vladimir

AU - Çarkoglu, Asli

AU - Radwan, Ghada Nasr

AU - El-Rabbat, Maha

AU - Cohen, Joanna E

AU - Strickland, Paul Timothy

AU - Breysse, Patrick N

AU - Navas Acien, Ana

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N2 - Background: Most smoke-free legislation to reduce secondhand smoke (SHS) exposure exempts waterpipe (hookah) smoking venues. Few studies have examined SHS exposure in waterpipe venues and their employees. Methods: We surveyed 276 employees of 46 waterpipe tobacco venues in Istanbul, Moscow, and Cairo. We interviewed venue managers and employees and collected biological samples from employees to measure exhaled carbon monoxide (CO), hair nicotine, saliva cotinine, urine cotinine, urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and urine 1-hydroxypyrene glucuronide (1-OHPG). We estimated adjusted geometric mean ratios (GMR) of each SHS biomarker by employee characteristics and indoor air SHS measures. Results: There were 73 nonsmoking employees and 203 current smokers of cigarettes or waterpipe. In nonsmokers, the median (interquartile) range concentrations of SHS biomarkers were 1.1 (0.2, 40.9) μg/g creatinine urine cotinine, 5.5 (2, 15) ng/mL saliva cotinine, 0.95 (0.36, 5.02) ng/mg hair nicotine, 1.48 (0.98, 3.97) pg/mg creatinine urine NNAL, 0.54 (0.25, 0.97) pmol/mg creatinine urine 1-OHPG, and 1.67 (1.33, 2.33) ppm exhaled CO. An 8-hour increase in work hours was associated with higher urine cotinine (GMR: 1.68, 95% CI: 1.20, 2.37) and hair nicotine (GMR: 1.22, 95% CI: 1.05, 1.43). Lighting waterpipes was associated with higher saliva cotinine (GMR: 2.83, 95% CI: 1.05, 7.62).

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