Biomarkers in neoplastic neuropathology

Fausto J Rodriguez, Cheng Ying Ho

Research output: Book/ReportBook

Abstract

This book is a rich source of information on biomarkers applicable to the pathology of neoplastic disorders of the brain. Thorough descriptions are provided of the techniques currently available for clinical and experimental evaluation of biomarkers in brain neoplasms, including in situ hybridization, array-based methods, methylation profiling, next-generation sequencing, and practical gene panels. Incorporation of multiple biomarkers in the development of molecular subgroups with biologic and therapeutic relevance is also discussed. A section on biobanking covers the equally important topic of optimal preservation of tissue and includes consideration of ethical considerations raised by the use of tissue obtained in clinical settings. The closing section discusses the major categories of neoplastic disorders involving the nervous system, with emphasis on diagnostic, prognostic, and predictive biomarkers used in the pathologic evaluation of different types of brain tumor.

Original languageEnglish (US)
PublisherSpringer International Publishing
Number of pages98
ISBN (Electronic)9783319209319
ISBN (Print)9783319209302
DOIs
StatePublished - Jan 1 2016

Fingerprint

Biomarkers
Brain
Brain Neoplasms
Tissue
Tissue Preservation
Methylation
Neurology
Brain Diseases
Pathology
Nervous System Diseases
In Situ Hybridization
Tumors
Genes
Neuropathology
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Biomarkers in neoplastic neuropathology. / Rodriguez, Fausto J; Ho, Cheng Ying.

Springer International Publishing, 2016. 98 p.

Research output: Book/ReportBook

Rodriguez, Fausto J ; Ho, Cheng Ying. / Biomarkers in neoplastic neuropathology. Springer International Publishing, 2016. 98 p.
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