TY - JOUR
T1 - Biological versus ambient exposure monitoring of creosote facility workers
AU - Borak, Jonathan
AU - Sirianni, Greg
AU - Cohen, Howard
AU - Chemerynski, Susan
AU - Jongeneelen, Frans
PY - 2002/1/1
Y1 - 2002/1/1
N2 - Traditional methods for monitoring occupational creosote exposure have focused on inhalation. However, there is evidence that dermal exposure contributes importantly to total systemic dose, as measured by biological monitoring methods. This study was conducted to further characterize the relationships between inhalation and dermal exposures to creosote, and to compare traditional ambient exposure monitoring versus biological monitoring in 36 creosote-exposed wood treatment workers. Full-shift personal air samples were obtained, along with post-shift and next-day urine measurements for 1-hydroxypyrene. There was little or no correlation between airborne measures and urinary 1-hydroxypyrene (r2 = 0.05 to 0.35). More than 90% of 1-hydroxypyrene could be attributed to dermal exposure. These data indicate that traditional monitoring methods may be inappropriate for creosote workers, raising concerns about the adequacy of methods currently mandated by the Occupational Safety and Health Administration.
AB - Traditional methods for monitoring occupational creosote exposure have focused on inhalation. However, there is evidence that dermal exposure contributes importantly to total systemic dose, as measured by biological monitoring methods. This study was conducted to further characterize the relationships between inhalation and dermal exposures to creosote, and to compare traditional ambient exposure monitoring versus biological monitoring in 36 creosote-exposed wood treatment workers. Full-shift personal air samples were obtained, along with post-shift and next-day urine measurements for 1-hydroxypyrene. There was little or no correlation between airborne measures and urinary 1-hydroxypyrene (r2 = 0.05 to 0.35). More than 90% of 1-hydroxypyrene could be attributed to dermal exposure. These data indicate that traditional monitoring methods may be inappropriate for creosote workers, raising concerns about the adequacy of methods currently mandated by the Occupational Safety and Health Administration.
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U2 - 10.1097/00043764-200204000-00011
DO - 10.1097/00043764-200204000-00011
M3 - Article
C2 - 11977417
AN - SCOPUS:0036123526
VL - 44
SP - 310
EP - 319
JO - Journal of Occupational and Environmental Medicine
JF - Journal of Occupational and Environmental Medicine
SN - 1076-2752
IS - 4
ER -