@article{f976714b023641acac801876002efd2c,
title = "Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework",
abstract = "Many biological subdisciplines that regularly assess dose-response relationships have identified an evolutionarily conserved process in which a low dose of a stressful stimulus activates an adaptive response that increases the resistance of the cell or organism to a moderate to severe level of stress. Due to a lack of frequent interaction among scientists in these many areas, there has emerged a broad range of terms that describe such dose-response relationships. This situation has become problematic because the different terms describe a family of similar biological responses (e.g., adaptive response, preconditioning, hormesis), adversely affecting interdisciplinary communication, and possibly even obscuring generalizable features and central biological concepts. With support from scientists in a broad range of disciplines, this article offers a set of recommendations we believe can achieve greater conceptual harmony in dose-response terminology, as well as better understanding and communication across the broad spectrum of biological disciplines.",
keywords = "Adaptive response, Biphasic, Conditioning, Dose-response, Hormesis, Postconditioning, Preconditioning, Stress response, U-shaped",
author = "Calabrese, {Edward J.} and Bachmann, {Kenneth A.} and Bailer, {A. John} and Bolger, {P. Michael} and Jonathan Borak and Lu Cai and Nina Cedergreen and Cherian, {M. George} and Chiueh, {Chuang C.} and Clarkson, {Thomas W.} and Cook, {Ralph R.} and Diamond, {David M.} and Doolittle, {David J.} and Dorato, {Michael A.} and Duke, {Stephen O.} and Ludwig Feinendegen and Gardner, {Donald E.} and Hart, {Ronald W.} and Hastings, {Kenneth L.} and Hayes, {A. Wallace} and Hoffmann, {George R.} and Ives, {John A.} and Zbigniew Jaworowski and Johnson, {Thomas E.} and Jonas, {Wayne B.} and Kaminski, {Norbert E.} and Keller, {John G.} and Klaunig, {James E.} and Knudsen, {Thomas B.} and Kozumbo, {Walter J.} and Teresa Lettieri and Liu, {Shu Zheng} and Andre Maisseu and Maynard, {Kenneth I.} and Masoro, {Edward J.} and McClellan, {Roger O.} and Mehendale, {Harihara M.} and Carmel Mothersill and Newlin, {David B.} and Nigg, {Herbert N.} and Oehme, {Frederick W.} and Phalen, {Robert F.} and Philbert, {Martin A.} and Rattan, {Suresh I.S.} and Riviere, {Jim E.} and Joseph Rodricks and Sapolsky, {Robert M.} and Scott, {Bobby R.} and Colin Seymour and Sinclair, {David A.} and Joan Smith-Sonneborn and Snow, {Elizabeth T.} and Linda Spear and Stevenson, {Donald E.} and Yolene Thomas and Maurice Tubiana and Williams, {Gary M.} and Mattson, {Mark P.}",
year = "2007",
month = jul,
day = "1",
doi = "10.1016/j.taap.2007.02.015",
language = "English (US)",
volume = "222",
pages = "122--128",
journal = "Toxicology and Applied Pharmacology",
issn = "0041-008X",
publisher = "Academic Press Inc.",
number = "1",
}