TY - JOUR
T1 - Biologic grafts and synthetic meshes in pelvic reconstructive surgery
AU - Chen, Chi Chiung Grace
AU - Ridgeway, Beri
AU - Paraiso, Marie Fidela R.
PY - 2007/6
Y1 - 2007/6
N2 - Despite the lack of evidence, augmenting pelvic organ prolapse surgery with biologic graft or synthetic mesh is increasing. The objective of this review is to examine the available grafts and meshes and discuss the current data addressing the use of these implants in correction of apical, anterior, and posterior prolapse. Most of the studies are retrospective with few randomized controlled trials. There is level I evidence suggesting that repair of apical prolapse with abdominal sacral colpopexy using synthetic mesh results in improved outcomes. However, most of the data concerning graft or mesh incorporation in anterior or posterior repairs do not support augmentation with prosthesis.
AB - Despite the lack of evidence, augmenting pelvic organ prolapse surgery with biologic graft or synthetic mesh is increasing. The objective of this review is to examine the available grafts and meshes and discuss the current data addressing the use of these implants in correction of apical, anterior, and posterior prolapse. Most of the studies are retrospective with few randomized controlled trials. There is level I evidence suggesting that repair of apical prolapse with abdominal sacral colpopexy using synthetic mesh results in improved outcomes. However, most of the data concerning graft or mesh incorporation in anterior or posterior repairs do not support augmentation with prosthesis.
KW - Biologic graft
KW - Pelvic organ prolapse
KW - Synthetic mesh
UR - http://www.scopus.com/inward/record.url?scp=34249879857&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34249879857&partnerID=8YFLogxK
U2 - 10.1097/GRF.0b013e31804b184c
DO - 10.1097/GRF.0b013e31804b184c
M3 - Review article
C2 - 17513926
AN - SCOPUS:34249879857
SN - 0009-9201
VL - 50
SP - 383
EP - 411
JO - Clinical obstetrics and gynecology
JF - Clinical obstetrics and gynecology
IS - 2
ER -